Laplante P, Niyonsenga T, Delisle E, Vanasse N, Vanasse A, Grant A M, Xhignesse M
Département de médecine de famille, l'Université de Sherbrooke à Sherbrooke, Qué.
Can Fam Physician. 1998 Feb;44:306-12.
To describe the treatment of hypertension, alone or in combination with associated conditions, by a group of general practitioners in the FAMUS network and to compare these treatment patterns to the recommendations of the Canadian Hypertension Society Consensus. DESIGN: Descriptive study based on data collected by 233 physicians in the FAMUS provincial register on hypertensive patients treated in 1996. PARTICIPANTS: Developed between 1992 and 1996, the register contains 52,505 patients, 9,094 of whom have high blood pressure. These patients consulted their general practitioners for a complete examination. The data concern the risk factors for cardiovascular disease and include the list of medications prescribed. MAIN OUTCOME MEASURES: Evaluation of the proportions in which various classes of medications were prescribed, and the most common combinations in relation to the presence or absence of associated conditions. RESULTS: Of the 4,049 hypertensive patients seen in 1996, 50.2% were treated with one medication; 32.9% were treated with more than one medication; and 16.9% received no antihypertensive medication. The most frequently prescribed medications were calcium channel blockers (26.1%), followed by diuretics (25.3%), angiotensin-converting enzyme inhibitors (24.3%), and beta-blockers (20.0%). Other agents made up the remaining 4.3% of prescriptions. The proportions were similar for patients without complications who received one medication. CONCLUSIONS: Results of this study suggest that the new molecules are widely used and that treatment patterns differ from the recommendations of the Canadian Hypertension Society Consensus, particularly in the absence of associated conditions.
描述FAMUS网络中的一组全科医生对高血压单独或合并相关病症的治疗情况,并将这些治疗模式与加拿大高血压协会共识的建议进行比较。
基于FAMUS省级登记册中233名医生收集的1996年接受治疗的高血压患者数据的描述性研究。
该登记册于1992年至1996年间建立,包含52,505名患者,其中9,094名患有高血压。这些患者向他们的全科医生进行了全面检查。数据涉及心血管疾病的危险因素,并包括所开药物清单。
评估各类药物的处方比例,以及与是否存在相关病症有关的最常见药物组合。
在1996年就诊的4,049名高血压患者中,50.2%接受了一种药物治疗;32.9%接受了一种以上药物治疗;16.9%未接受抗高血压药物治疗。最常开具的药物是钙通道阻滞剂(26.1%),其次是利尿剂(25.3%)、血管紧张素转换酶抑制剂(24.3%)和β受体阻滞剂(20.0%)。其他药物占处方总数的4.3%。接受一种药物治疗的无并发症患者的比例相似。
本研究结果表明,新分子被广泛使用,治疗模式与加拿大高血压协会共识的建议不同,特别是在无相关病症的情况下。