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本文引用的文献

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N Engl J Med. 1993 Apr 1;328(13):914-21. doi: 10.1056/NEJM199304013281303.
3
Report of the Canadian Hypertension Society Consensus Conference: 3. Pharmacologic treatment of essential hypertension.加拿大高血压协会共识会议报告:3. 原发性高血压的药物治疗
CMAJ. 1993 Sep 1;149(5):575-84.
4
Treatment of Mild Hypertension Study. Final results. Treatment of Mild Hypertension Study Research Group.轻度高血压治疗研究。最终结果。轻度高血压治疗研究组
JAMA. 1993 Aug 11;270(6):713-24.
5
Implementation of a province-wide computerized network in Quebec: the FAMUS Project.魁北克省全省计算机网络的实施:FAMUS项目。
MD Comput. 1995 Jan-Feb;12(1):45-9.
6
Management of the postmyocardial infarction patient: a consensus report--revision of 1991 CCS guidelines.
Can J Cardiol. 1995 Jun;11(6):477-86.
7
Treatment preferences, return visit planning and factors affecting hypertension practice amongst general practitioners and internal medicine specialists (the General Practitioner Hypertension Practice Study).
J Intern Med. 1995 May;237(5):473-8. doi: 10.1111/j.1365-2796.1995.tb00872.x.
8
Temporal patterns of antihypertensive medication use among older adults, 1989 through 1992. An effect of the major clinical trials on clinical practice?
JAMA. 1995 May 10;273(18):1436-8.
9
Reported treatment of hypertension by family physicians in Sweden and Minnesota: a physician survey of practice habits.瑞典和明尼苏达州家庭医生对高血压的报告治疗情况:一项关于执业习惯的医生调查
J Intern Med. 1995 Sep;238(3):215-21. doi: 10.1111/j.1365-2796.1995.tb00925.x.
10
Discontinuation of and changes in treatment after start of new courses of antihypertensive drugs: a study of a United Kingdom population.新疗程抗高血压药物开始治疗后的停药及治疗变化:对英国人群的一项研究
BMJ. 1995 Jul 29;311(7000):293-5. doi: 10.1136/bmj.311.7000.293.

1996年高血压的治疗模式。来自舍布鲁克大学魁北克家庭医疗登记处的数据

[Treatment patterns of hypertension in 1996. Data from the Quebec Family Practice, University of Sherbrooke registry].

作者信息

Laplante P, Niyonsenga T, Delisle E, Vanasse N, Vanasse A, Grant A M, Xhignesse M

机构信息

Département de médecine de famille, l'Université de Sherbrooke à Sherbrooke, Qué.

出版信息

Can Fam Physician. 1998 Feb;44:306-12.

PMID:9512834
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2277604/
Abstract

OBJECTIVE

To describe the treatment of hypertension, alone or in combination with associated conditions, by a group of general practitioners in the FAMUS network and to compare these treatment patterns to the recommendations of the Canadian Hypertension Society Consensus. DESIGN: Descriptive study based on data collected by 233 physicians in the FAMUS provincial register on hypertensive patients treated in 1996. PARTICIPANTS: Developed between 1992 and 1996, the register contains 52,505 patients, 9,094 of whom have high blood pressure. These patients consulted their general practitioners for a complete examination. The data concern the risk factors for cardiovascular disease and include the list of medications prescribed. MAIN OUTCOME MEASURES: Evaluation of the proportions in which various classes of medications were prescribed, and the most common combinations in relation to the presence or absence of associated conditions. RESULTS: Of the 4,049 hypertensive patients seen in 1996, 50.2% were treated with one medication; 32.9% were treated with more than one medication; and 16.9% received no antihypertensive medication. The most frequently prescribed medications were calcium channel blockers (26.1%), followed by diuretics (25.3%), angiotensin-converting enzyme inhibitors (24.3%), and beta-blockers (20.0%). Other agents made up the remaining 4.3% of prescriptions. The proportions were similar for patients without complications who received one medication. CONCLUSIONS: Results of this study suggest that the new molecules are widely used and that treatment patterns differ from the recommendations of the Canadian Hypertension Society Consensus, particularly in the absence of associated conditions.

摘要

目的

描述FAMUS网络中的一组全科医生对高血压单独或合并相关病症的治疗情况,并将这些治疗模式与加拿大高血压协会共识的建议进行比较。

设计

基于FAMUS省级登记册中233名医生收集的1996年接受治疗的高血压患者数据的描述性研究。

参与者

该登记册于1992年至1996年间建立,包含52,505名患者,其中9,094名患有高血压。这些患者向他们的全科医生进行了全面检查。数据涉及心血管疾病的危险因素,并包括所开药物清单。

主要观察指标

评估各类药物的处方比例,以及与是否存在相关病症有关的最常见药物组合。

结果

在1996年就诊的4,049名高血压患者中,50.2%接受了一种药物治疗;32.9%接受了一种以上药物治疗;16.9%未接受抗高血压药物治疗。最常开具的药物是钙通道阻滞剂(26.1%),其次是利尿剂(25.3%)、血管紧张素转换酶抑制剂(24.3%)和β受体阻滞剂(20.0%)。其他药物占处方总数的4.3%。接受一种药物治疗的无并发症患者的比例相似。

结论

本研究结果表明,新分子被广泛使用,治疗模式与加拿大高血压协会共识的建议不同,特别是在无相关病症的情况下。