三维超声评估极低出生体重儿胼胝体的生物测量及其与神经发育结局的相关性
Biometry of the corpus callosum assessed by 3D ultrasound and its correlation to neurodevelopmental outcome in very low birth weight infants.
作者信息
Klebermass-Schrehof K, Aumüller S, Goeral K, Vergesslich-Rothschild K, Fuiko R, Brandstetter S, Berger A, Jilma B, Haiden N
机构信息
Department of Pediatrics and Adolescent Medicine, Division of Neonatology, Intensive Care and Neuropediatrics, Medical University of Vienna, Vienna, Austria.
Department of General Radiology and Pediatric Radiology, Medical University of Vienna, Vienna, Austria.
出版信息
J Perinatol. 2017 Apr;37(4):448-453. doi: 10.1038/jp.2016.231. Epub 2016 Dec 15.
OBJECTIVE
Several studies have shown a relation between the size of corpus callosum (CC) and outcome in preterm infants. Three-dimensional ultrasound (3D-US) offers new perspectives in cerebral imaging. To establish reference values for biometry of the CC in very low birth weight infants and to correlate these measurements to neurodevelopmental outcome at 5 years of age.
STUDY DESIGN
Forty-three preterm infants with a gestational age <32 weeks were included. Transfontanellar 3D-US measurements were obtained at nine different timepoints.
RESULTS
3D-US-based reference values for size, length, circumference and surface area of the CC could be established. Measurements at term-equivalent age showed a correlation to neurodevelopment outcome.
CONCLUSION
Reliable biometric data of the CC can be established in preterm infants by 3D-US and correlate with neurodevelopmental outcome.
目的
多项研究表明早产儿胼胝体（CC）大小与预后之间存在关联。三维超声（3D-US）为脑成像提供了新视角。本研究旨在建立极低出生体重儿CC生物测量的参考值，并将这些测量值与5岁时的神经发育结局相关联。
研究设计
纳入43例孕周<32周的早产儿。在九个不同时间点进行经囟门3D-US测量。
结果
可建立基于3D-US的CC大小、长度、周长和表面积的参考值。足月等效年龄时的测量结果与神经发育结局相关。
结论
通过3D-US可在早产儿中建立可靠的CC生物测量数据，并与神经发育结局相关联。
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