[Changes in the periodontium in prolonged hypodynamia and the use of biphosphanates and silatrane for the purpose of their prevention].

Forty-day hypodynamia caused by "hanging" rats on a special stand with discontinuance of the status function of the hind limbs and partial maintenance of the supporting function of the front limbs led to progressive atrophic changes in the alveolar process of the animals' jaws, which were accompanied by changes of the mineral phase manifested by diminished parameter of microfirmness. Atrophy of the alveolar process in hypodynamia was attended by marked tissue changes in the form of dentogingival pockets, widening of the periodontal fissure, and intensified resorption of the interradicular and interalveolar septa of the molars.