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[长期动力不足状态下牙周组织的变化以及使用双膦酸盐和硅氮烷进行预防的研究]

[Changes in the periodontium in prolonged hypodynamia and the use of biphosphanates and silatrane for the purpose of their prevention].

作者信息

Volozhin A I, Amel'kina G V

出版信息

Patol Fiziol Eksp Ter. 1989 May-Jun(3):72-5.

PMID:2797906
Abstract

Forty-day hypodynamia caused by "hanging" rats on a special stand with discontinuance of the status function of the hind limbs and partial maintenance of the supporting function of the front limbs led to progressive atrophic changes in the alveolar process of the animals' jaws, which were accompanied by changes of the mineral phase manifested by diminished parameter of microfirmness. Atrophy of the alveolar process in hypodynamia was attended by marked tissue changes in the form of dentogingival pockets, widening of the periodontal fissure, and intensified resorption of the interradicular and interalveolar septa of the molars.

摘要

将大鼠置于特殊支架上“悬吊”40天,后肢状态功能中断,前肢支撑功能部分保留,导致动物颌骨牙槽突出现进行性萎缩性变化,同时伴有矿化相改变,表现为微硬度参数降低。动力不足时牙槽突萎缩伴有明显的组织变化,如牙齦袋形成、牙周间隙增宽以及磨牙根间和牙槽间隔的吸收加剧。

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