Huang Weihua, Yin Changhong, Zhuge Jian, Farooq Taliya, Yoon Esther C, Nolan Sheila M, Chen Donald, Fallon John T, Wang Guiqing
Department of Pathology, New York Medical College, Valhalla, New York, USA.
Department of Pathology and Clinical Laboratories, Westchester Medical Center, Valhalla, New York, USA.
Genome Announc. 2016 Dec 15;4(6):e01394-16. doi: 10.1128/genomeA.01394-16.
Complete genome sequences of nine enterovirus D68 (EV-D68) strains from patients in New York were obtained in 2016 by metagenomic next-generation sequencing. Comparative genomic analysis suggests that a new subclade B3, with ~4.5% nucleotide divergence from subclade B1 strains causing the 2014 outbreak, is circulating in the United States in 2016.
2016年,通过宏基因组新一代测序获得了来自纽约患者的9株肠道病毒D68(EV-D68)毒株的全基因组序列。比较基因组分析表明,一个新的B3亚分支在2016年在美国传播,它与导致2014年疫情的B1亚分支毒株有~4.5%的核苷酸差异。