Kalha Anmol S
ITS Dental College, Hospital and Research Center, Greater Noida, NCR, India.
Evid Based Dent. 2016 Dec;17(4):105-106. doi: 10.1038/sj.ebd.6401200.
Data sourcesCochrane Oral Health Group's Trials Register, Cochrane Central Register of Controlled Trials (CENTRAL), Medline, Embase, US National Institutes of Health Trials Registry and The World Health Organization (WHO) Clinical Trials Registry Platform, abstracts from the British Orthodontic Conference, the European Orthodontic Conference and the International Association for Dental Research (IADR) from 2011 to 2015 and the bibliographies of identified studies.Study selectionRandomised controlled trials (RCTs) involving children and adults who had had retainers fitted or adjunctive procedures undertaken to prevent relapse following orthodontic treatment with braces were considered.Data extraction and synthesisTwo reviewers independently selected studies, abstracted data and assessed study quality. For continuous data mean differences (MD) with 95% confidence intervals (CI) were calculated with ratios (RR) and 95% CI for dichotomous outcomes.ResultsFifteen studies involving a total of 1722 patients were included. Seven studies were considered to be at high risk of bias, four at low risk and four at unclear risk. For removable retainers versus fixed retainers (three studies) there was low quality evidence that thermoplastic removable retainers provided slightly poorer stability in the lower arch than multistrand fixed retainers: MD (Little's Irregularity Index, 0 mm is stable) 0.6 mm (95% CI 0.17 to 1.03) and of less gingival bleeding with removable retainers: RR 0.53 (95%CI; 0.31 to 0.88). Patients found fixed retainers more acceptable to wear, with a mean difference on a visual analogue scale (VAS; 0 to 100; 100 being very satisfied) of -12.84 (95% CI -7.09 to -18.60).For different types of fixed retainers (four studies) data from three studies (228 patients) comparing polyethylene ribbon bonded retainer versus multistrand retainer were pooled showing no evidence of a difference in failure rates. RR = 1.10 (95%CI; 0.77 to 1.57).Pooled data from two trials (174 patients) comparing the same types of upper fixed retainers, showed a similar finding: RR =1.25 (95%CI; 0.87 to 1.78).For different types of removable retainers (eight studies) one study at low risk of bias comparing upper and lower part-time thermoplastic versus full-time thermoplastic retainers showed no evidence of a difference in relapse (graded moderate quality evidence). Another study, comparing part-time and full-time wear of lower Hawley retainers, found no evidence of any difference in relapse (low quality evidence). Two studies at high risk of bias suggested that stability was better in the lower arch for thermoplastic retainers versus Hawley, and for thermoplastic full-time versus Begg (fulltime) (both low quality evidence). In one study, participants wearing Hawley retainers reported more embarrassment more often than participants wearing thermoplastic retainers: RR 2.42 (95% CI 1.30 to 4.49; one trial, 348 participants, high risk of bias, low quality evidence). They also found Hawley retainers harder to wear. There was conflicting evidence about survival rates of Hawley and thermoplastic retainers.For combination of upper thermoplastic and lower bonded versus upper thermoplastic with lower adjunctive procedures versus positioner (one study) there was no evidence of a difference in relapse between the combination of an upper thermoplastic and lower canine to canine bonded retainer and the combination of an upper thermoplastic retainer and lower interproximal stripping, without a lower retainer. Both these approaches are better than using a positioner as a retainer.ConclusionsWe did not find any evidence that wearing thermoplastic retainers fulltime provides greater stability than wearing them part-time, but this was assessed in only a small number of participants. Overall, there is insufficient high quality evidence to make recommendations on retention procedures for stabilising tooth position after treatment with orthodontic braces. Further high quality RCTs are needed.
数据来源
Cochrane口腔健康小组试验注册库、Cochrane对照试验中央注册库(CENTRAL)、医学期刊数据库(Medline)、荷兰医学文摘数据库(Embase)、美国国立卫生研究院试验注册库以及世界卫生组织(WHO)临床试验注册平台、2011年至2015年英国正畸会议、欧洲正畸会议和国际牙科研究协会(IADR)的摘要以及已识别研究的参考文献。
研究选择
纳入涉及佩戴保持器或进行辅助程序以防止正畸治疗后复发的儿童和成人的随机对照试验(RCT)。
数据提取与综合
两名审查员独立选择研究、提取数据并评估研究质量。对于连续性数据,计算平均差(MD)及95%置信区间(CI);对于二分结果,计算比值比(RR)及95%CI。
结果
共纳入15项研究,涉及1722例患者。7项研究被认为存在高偏倚风险,4项为低偏倚风险,4项风险不明。对于可摘保持器与固定保持器(三项研究),低质量证据表明,热塑性可摘保持器在下牙弓的稳定性略低于多股固定保持器:MD(Little不规则指数,0mm为稳定)为0.6mm(95%CI 0.17至1.03);可摘保持器的牙龈出血较少:RR 0.53(95%CI;0.31至0.88)。患者发现固定保持器佩戴起来更可接受,视觉模拟量表(VAS;0至100;100表示非常满意)的平均差为-12.84(95%CI -7.09至-18.60)。
对于不同类型的固定保持器(四项研究),三项研究(228例患者)比较聚乙烯带粘结保持器与多股保持器的数据合并后显示,失败率无差异证据。RR = 1.10(95%CI;0.77至1.57)。
两项试验(174例患者)比较相同类型上固定保持器的合并数据显示类似结果:RR =1.25(95%CI;0.87至1.78)。
对于不同类型的可摘保持器(八项研究),一项低偏倚风险研究比较上下部分时间佩戴热塑性保持器与全时间佩戴热塑性保持器,未发现复发有差异证据(中等质量证据分级)。另一项研究比较下霍利保持器的部分时间和全时间佩戴,未发现复发有任何差异证据(低质量证据)。两项高偏倚风险研究表明,热塑性保持器在下牙弓的稳定性优于霍利保持器,热塑性全时间佩戴保持器优于Begg(全时间)保持器(均为低质量证据)。在一项研究中,佩戴霍利保持器的参与者比佩戴热塑性保持器的参与者更常报告尴尬:RR 2.42(95%CI 1.30至4.49;一项试验,348名参与者,高偏倚风险,低质量证据)。他们还发现霍利保持器更难佩戴。关于霍利保持器和热塑性保持器的生存率存在相互矛盾的证据。
对于上热塑性保持器与下粘结保持器组合、上热塑性保持器与下辅助程序组合与定位器(一项研究),上热塑性保持器与下犬牙至犬牙粘结保持器组合以及上热塑性保持器与下邻面去釉组合(无下保持器)之间在复发方面无差异证据。这两种方法均优于使用定位器作为保持器。
结论
我们未发现任何证据表明全时间佩戴热塑性保持器比部分时间佩戴能提供更高的稳定性,但仅在少数参与者中进行了评估。总体而言,缺乏高质量证据来推荐正畸治疗后稳定牙齿位置的保持程序。需要进一步的高质量RCT。