Littlewood Simon J, Millett Declan T, Doubleday Bridget, Bearn David R, Worthington Helen V
Orthodontic Department, St Luke's Hospital, Little Horton Lane, Bradford, West Yorkshire, UK, BD5 0NA.
Cochrane Database Syst Rev. 2016 Jan 29;2016(1):CD002283. doi: 10.1002/14651858.CD002283.pub4.
Retention is the phase of orthodontic treatment that attempts to keep teeth in the corrected positions after treatment with orthodontic braces. Without a phase of retention, there is a tendency for teeth to return to their initial position (relapse). To prevent relapse, almost every person who has orthodontic treatment will require some type of retention.
To evaluate the effects of different retention strategies used to stabilise tooth position after orthodontic braces.
We searched the following databases: the Cochrane Oral Health Group's Trials Register (to 26 January 2016), the Cochrane Central Register of Controlled Trials (CENTRAL) (2015, Issue 12), MEDLINE via Ovid (1946 to 26 January 2016) and EMBASE via Ovid (1980 to 26 January 2016). We searched for ongoing trials in the US National Institutes of Health Trials Register (ClinicalTrials.gov) and the World Health Organization (WHO) International Clinical Trials Registry Platform. We applied no language or date restrictions in the searches of the electronic databases. We contacted authors of randomised controlled trials (RCTs) to help identify any unpublished trials.
RCTs involving children and adults who had had retainers fitted or adjunctive procedures undertaken to prevent relapse following orthodontic treatment with braces.
Two review authors independently screened eligible studies, assessed the risk of bias in the trials and extracted data. The outcomes of interest were: how well the teeth were stabilised, failure of retainers, adverse effects on oral health and participant satisfaction. We calculated mean differences (MD) with 95% confidence intervals (CI) for continuous data and risk ratios (RR) with 95% CI for dichotomous outcomes. We conducted meta-analyses when studies with similar methodology reported the same outcome. We prioritised reporting of Little's Irregularity Index to measure relapse.
We included 15 studies (1722 participants) in the review. There are also four ongoing studies and four studies await classification. The 15 included studies evaluated four comparisons: removable retainers versus fixed retainers (three studies); different types of fixed retainers (four studies); different types of removable retainers (eight studies); and one study compared a combination of upper thermoplastic and lower bonded versus upper thermoplastic with lower adjunctive procedures versus positioner. Four studies had a low risk of bias, four studies had an unclear risk of bias and seven studies had a high risk of bias. Removable versus fixed retainers Thermoplastic removable retainers provided slightly poorer stability in the lower arch than multistrand fixed retainers: MD (Little's Irregularity Index, 0 mm is stable) 0.6 mm (95% CI 0.17 to 1.03). This was based on one trial with 84 participants that was at high risk of bias; it was low quality evidence. Results on retainer failure were inconsistent. There was evidence of less gingival bleeding with removable retainers: RR 0.53 (95% CI 0.31 to 0.88; one trial, 84 participants, high risk of bias, low quality evidence), but participants found fixed retainers more acceptable to wear, with a mean difference on a visual analogue scale (VAS; 0 to 100; 100 being very satisfied) of -12.84 (95% CI -7.09 to -18.60). Fixed versus fixed retainersThe studies did not report stability, adverse effects or participant satisfaction. It was possible to pool the data on retention failure from three trials that compared polyethylene ribbon bonded retainer versus multistrand retainer in the lower arch with an RR of 1.10 (95% CI 0.77 to 1.57; moderate heterogeneity; three trials, 228 participants, low quality evidence). There was no evidence of a difference in failure rates. It was also possible to pool the data from two trials that compared the same types of upper fixed retainers, with a similar finding: RR 1.25 (95% CI 0.87 to 1.78; low heterogeneity; two trials, 174 participants, low quality evidence). Removable versus removable retainersOne study at low risk of bias comparing upper and lower part-time thermoplastic versus full-time thermoplastic retainer showed no evidence of a difference in relapse (graded moderate quality evidence). Another study, comparing part-time and full-time wear of lower Hawley retainers, found no evidence of any difference in relapse (low quality evidence). Two studies at high risk of bias suggested that stability was better in the lower arch for thermoplastic retainers versus Hawley, and for thermoplastic full-time versus Begg (full-time) (both low quality evidence).In one study, participants wearing Hawley retainers reported more embarrassment more often than participants wearing thermoplastic retainers: RR 2.42 (95% CI 1.30 to 4.49; one trial, 348 participants, high risk of bias, low quality evidence). They also found Hawley retainers harder to wear. There was conflicting evidence about survival rates of Hawley and thermoplastic retainers. Other retainer comparisonsAnother study with a low risk of bias looked at three different approaches to retention for people with crowding, but normal jaw relationships. The study found that there was no evidence of a difference in relapse between the combination of an upper thermoplastic and lower canine to canine bonded retainer and the combination of an upper thermoplastic retainer and lower interproximal stripping, without a lower retainer. Both these approaches are better than using a positioner as a retainer.
AUTHORS' CONCLUSIONS: We did not find any evidence that wearing thermoplastic retainers full-time provides greater stability than wearing them part-time, but this was assessed in only a small number of participants.Overall, there is insufficient high quality evidence to make recommendations on retention procedures for stabilising tooth position after treatment with orthodontic braces. Further high quality RCTs are needed.
保持是正畸治疗的一个阶段,旨在在用正畸矫治器治疗后将牙齿保持在矫正后的位置。如果没有保持阶段,牙齿有回到初始位置(复发)的趋势。为防止复发,几乎每个接受正畸治疗的人都需要某种类型的保持器。
评估用于稳定正畸矫治器治疗后牙齿位置的不同保持策略的效果。
我们检索了以下数据库:Cochrane口腔健康组试验注册库(至2016年1月26日)、Cochrane对照试验中心注册库(CENTRAL)(2015年第12期)、通过Ovid检索的MEDLINE(1946年至2016年1月26日)以及通过Ovid检索的EMBASE(1980年至2016年1月26日)。我们在美国国立卫生研究院试验注册库(ClinicalTrials.gov)和世界卫生组织(WHO)国际临床试验注册平台中检索正在进行的试验。在电子数据库检索中未应用语言或日期限制。我们联系了随机对照试验(RCT)的作者以帮助识别任何未发表的试验。
涉及佩戴保持器或进行辅助程序以防止正畸矫治器治疗后复发的儿童和成人的RCT。
两位综述作者独立筛选符合条件的研究,评估试验中的偏倚风险并提取数据。感兴趣的结局包括:牙齿稳定的程度、保持器失败、对口腔健康的不良影响以及参与者满意度。对于连续数据,我们计算了95%置信区间(CI)的平均差(MD),对于二分结局,计算了95%CI的风险比(RR)。当方法相似的研究报告相同结局时,我们进行了荟萃分析。我们优先报告用于测量复发的Little不规则指数。
我们在综述中纳入了15项研究(1722名参与者)。还有4项正在进行的研究,4项研究等待分类。纳入的15项研究评估了4种比较:可摘保持器与固定保持器(3项研究);不同类型的固定保持器(4项研究);不同类型的可摘保持器(8项研究);1项研究比较了上热塑性和下粘结保持器组合与上热塑性和下辅助程序组合与定位器。4项研究偏倚风险低,4项研究偏倚风险不明确,7项研究偏倚风险高。可摘与固定保持器热塑性可摘保持器在下牙弓中的稳定性略逊于多股固定保持器:MD(Little不规则指数,0mm为稳定)0.6mm(9%CI0.17至1.03)。这基于一项有84名参与者的试验,该试验偏倚风险高;这是低质量证据。关于保持器失败的结果不一致。有证据表明可摘保持器导致的牙龈出血较少:RR0.53(95%CI0.31至0.88;一项试验,84名参与者,偏倚风险高,低质量证据),但参与者发现固定保持器佩戴起来更可接受,在视觉模拟量表(VAS;0至100;100表示非常满意)上的平均差为-12.84(95%CI-7.09至-18.60)。固定与固定保持器这些研究未报告稳定性、不良反应或参与者满意度。可以汇总三项比较下牙弓中聚乙烯带粘结保持器与多股保持器的试验中的保持失败数据,RR为1.10(95%CI0.77至1.57;中度异质性;三项试验,228名参与者,低质量证据)。没有证据表明失败率存在差异。也可以汇总两项比较相同类型上固定保持器的试验数据,结果相似:RR1.25(95%CI0.87至1.);低异质性;两项试验,174名参与者,低质量证据)。可摘与可摘保持器一项偏倚风险低的研究比较了上下部分时间热塑性保持器与全时间热塑性保持器,未发现复发有差异的证据(中等质量分级证据)。另一项比较下Hawley保持器部分时间和全时间佩戴的研究,未发现复发有任何差异的证据(低质量证据)。两项偏倚风险高的研究表明,热塑性保持器在下牙弓中的稳定性优于Hawley保持器,热塑性全时间保持器优于Begg(全时间)保持器(均为低质量证据)。在一项研究中,佩戴Hawley保持器的参与者比佩戴热塑性保持器的参与者更常报告感到尴尬:RR2.42(95%CI1.30至4.49;一项试验,348名参与者,偏倚风险高,低质量证据)。他们还发现Hawley保持器更难佩戴。关于Hawley保持器和热塑性保持器的生存率存在相互矛盾的证据。其他保持器比较另一项偏倚风险低的研究针对拥挤但颌关系正常的人群研究了三种不同的保持方法。该研究发现,上热塑性和下犬牙间粘结保持器组合与上热塑性保持器和下邻面去釉组合(无下保持器)之间在复发方面没有证据表明存在差异。这两种方法都比使用定位器作为保持器更好。
我们没有发现任何证据表明全时间佩戴热塑性保持器比部分时间佩戴能提供更好的稳定性,但这仅在少数参与者中进行了评估。总体而言,没有足够的高质量证据就正畸矫治器治疗后稳定牙齿位置的保持程序提出建议。需要进一步的高质量RCT。