Zaruwa Moses Z, Ibok Nne I, Ibok Ibokabasi U, Onyenonachi Emmanuel C, Danchal C, Ahmed Aisha G, Ahmed Maryam U, Sudi Ismaila Y
Department of Chemistry, Faculty of Science, Adamawa State University, Mubi, Nigeria.
Department of Science Laboratory Technology, Federal Polytechnique, Mubi, Nigeria.
Biochem Insights. 2016 Dec 11;9:19-22. doi: 10.4137/BCI.S36143. eCollection 2016.
Africa is rich in a wide range of flora that are exploited as herbal medicines and remedies. Several diseases such as diabetes, diarrhea, dysentery and jaundice have been successfully managed using herbal medicines. Herbal decoctions or concoctions have been used as pain killers, antibiotics, and hematinics. This study evaluated the hematopoietic and biochemical properties of the stem bark of Del. in Wistar rats. Results showed that decoction has copiously high tannin and cardiac glycoside levels. Ingestion of the decoction by rats over a 16-day period significantly ( < 0.05) increased the body weights of rats by 22.4% in the -treated group. Hematological profiles showed raised levels of red blood cells, hemoglobin, packed cell volume, mean corpuscular volume, mean cell hemoglobin, mean cell hemoglobin concentration, and platelets, while biochemical parameters showed lower levels of alanine aminotransferase and aspartate aminotransferase, and slight increase in albumin and TP levels. We posit that the results justify the use of the stem bark of as a hematinic by traditional medical practitioners and show its relative safety. Further experiments are needed to evaluate its safety.
非洲拥有丰富多样的植物群，这些植物被用作草药和治疗方法。糖尿病、腹泻、痢疾和黄疸等多种疾病已通过草药成功治疗。草药煎剂或调和剂已被用作止痛药、抗生素和补血剂。本研究评估了德尔（Del.）茎皮在Wistar大鼠中的造血和生化特性。结果表明，煎剂中含有大量的单宁和强心苷。在16天的时间里，给大鼠喂食煎剂，治疗组大鼠的体重显著增加（<0.05），增幅为22.4%。血液学指标显示红细胞、血红蛋白、血细胞比容、平均红细胞体积、平均红细胞血红蛋白、平均红细胞血红蛋白浓度和血小板水平升高，而生化参数显示丙氨酸转氨酶和天冬氨酸转氨酶水平降低，白蛋白和总蛋白水平略有升高。我们认为，这些结果证明了传统医学从业者使用德尔茎皮作为补血剂的合理性，并表明了其相对安全性。需要进一步的实验来评估其安全性。
