Onitsuka H, Araki A, Torii Y, Tsukuda M, Murakami J, Ino A, Hashiguchi N, Masuda K
Nihon Igaku Hoshasen Gakkai Zasshi. 1989 Jul 25;49(7):915-20.
Ionic and non-ionic contrast media were compared for use in intravenous drip infusion excretory urography. Sixty consecutive cases were classified alternately into two groups, ionic and non-ionic, excluding cases which were known to have factors affecting contrast ability adversely, such as hydronephrosis, renal failure and so on. Each group consisted of 30 cases. A hundred ml of the ionic contrast medium (Diatrizoate--60% Urografin) or non-ionic contrast medium (Iopamidol--Iopamiron 300) was administered I.V. by drip infusion, each infusion taking less than 10 minutes, using a 18 G needle, and 0-minute, 10-minute and 20-minute films were obtained. Visibility of nephrogram, calyceal system, renal pelvis, ureters and bladder were evaluated, ranging from 0 to 3, by six radiologists who were not informed of the contrast medium used. Some detailed factors such as radiographic contrast and fullness of the collecting system and of the bladder were also analyzed. Visualization rate of the ureters was defined as the length of visualized ureters divided by the distance between the renal pelvis and the ureteral orifice of the bladder. There was no significant difference in visualization of nephrogram between the two groups. However, the non-ionic group was superior to the ionic group in visualization of the calyceal system and ureters with statistical significance, probably due to higher radiographic contrast of non-ionic medium. There was no statistical significance between the two groups, in fullness of the calyceal system and visualization rate of the ureters, whereas the ionic group was superior to the non-ionic group in fullness of the bladder.(ABSTRACT TRUNCATED AT 250 WORDS)
对离子型和非离子型造影剂在静脉滴注排泄性尿路造影中的应用进行了比较。将连续60例患者交替分为离子型和非离子型两组,排除已知有不利影响造影能力因素的病例,如肾积水、肾衰竭等。每组30例。通过静脉滴注给予100ml离子型造影剂(泛影葡胺 - 60%优维显)或非离子型造影剂(碘帕醇 - 碘必乐300),每次滴注时间少于10分钟,使用18G针头,并拍摄0分钟、10分钟和20分钟的X线片。由6名不知所用造影剂的放射科医生对肾图、肾盏系统、肾盂、输尿管和膀胱的显影情况进行评估,范围为0至3级。还分析了一些详细因素,如X线对比度以及集合系统和膀胱的充盈情况。输尿管显影率定义为显影输尿管的长度除以肾盂与膀胱输尿管口之间的距离。两组肾图显影情况无显著差异。然而,非离子型组在肾盏系统和输尿管显影方面优于离子型组,具有统计学意义,可能是由于非离子型造影剂的X线对比度更高。两组在肾盏系统充盈度和输尿管显影率方面无统计学差异,而离子型组在膀胱充盈度方面优于非离子型组。(摘要截短至250字)