Swerdlow Steven H
Division of Hematopathology, Department of Pathology, University of Pittsburgh School of Medicine, UPMC-Presbyterian, G-335, 200 Lothrop Street, Pittsburgh, PA 15213.
Semin Diagn Pathol. 2017 Jan;34(1):76-84. doi: 10.1053/j.semdp.2016.11.007. Epub 2016 Nov 29.
Primary cutaneous marginal zone lymphoma (CMZL) is one of the major primary B-cell lymphomas of skin. Two types are recognized: a more common class-chain switched CMZL, and a much less common IgM+ CMZL. The extremely indolent course, together with other features distinct from most other MALT lymphomas, has led some to question whether at least the class-switched cases should be considered an overt lymphoma.
原发性皮肤边缘区淋巴瘤(CMZL)是皮肤主要的原发性B细胞淋巴瘤之一。已确认有两种类型:一种是更常见的类别转换型CMZL,另一种是极少见的IgM+ CMZL。其病程极为惰性,加上其他与大多数其他黏膜相关淋巴组织淋巴瘤不同的特征,使得一些人质疑至少类别转换型病例是否应被视为一种明显的淋巴瘤。