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以冠状动脉口狭窄和主动脉瓣反流为表现的梅毒性主动脉炎。

Syphilitic Aortitis Presenting with Coronary Ostial Stenosis and Aortic Regurgitation.

作者信息

Jadeed Rayyan, Paarmann Ruth, Harringer Wolfgang, El-Essawi Aschraf

机构信息

Department Cardiology, Klinikum Braunschweig, Germany.

Department of Thoracic and Cardiovascular Surgery, Klinikum Braunschweig, Germany.

出版信息

J Heart Valve Dis. 2016 Jan;25(1):18-20.

Abstract

Bilateral coronary ostial stenosis without additional coronary artery involvement is a rare presentation of syphilitic aortitis, with most cases being identified post-mortem. Herein is presented a case of bilateral coronary ostial stenosis and aortic valve insufficiency caused by syphilitic aortitis without aneurysmal dilatation of the aorta. The patient underwent aortic root replacement and coronary artery bypass grafting. The intraoperative macroscopic findings raised the suspicion of an aortitis that was later confirmed to syphilitic aortitis on histological examination. It is of note that syphilis can be a cause of bilateral ostial stenosis in young adults with no predisposition to atherosclerosis, especially if combined with aortic insufficiency resulting from an isolated leaflet dysfunction.

摘要

双侧冠状动脉开口狭窄而无其他冠状动脉受累是梅毒性主动脉炎的一种罕见表现,大多数病例是在尸检时发现的。本文介绍了一例由梅毒性主动脉炎引起的双侧冠状动脉开口狭窄和主动脉瓣关闭不全,主动脉无瘤样扩张。患者接受了主动脉根部置换和冠状动脉搭桥术。术中宏观检查结果引发了对主动脉炎的怀疑,组织学检查后来证实为梅毒性主动脉炎。值得注意的是,梅毒可能是无动脉粥样硬化易患因素的年轻人双侧开口狭窄的一个原因,特别是如果合并由孤立瓣叶功能障碍导致的主动脉瓣关闭不全。

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