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大鼠的空间记忆:一项交叉验证研究。

Spatial memory in rats: a cross validation study.

作者信息

van Luijtelaar E L, van der Staay F J, Kerbusch J M

出版信息

Q J Exp Psychol B. 1989 Aug;41(3):287-306.

PMID:2798928
Abstract

Two experiments were performed to investigate whether two measures of spatial memory, working memory (WM) and reference memory (RM), can be generalized over learning situations. In the first experiment, outbred WU rats were used; in the second four inbred strains. In both experiments rats were given 50 training trials in both a holeboard and a high-sided radial maze: 4 out of 16 holes and 4 out of 8 arms were baited. The number of WM (revisits to baited holes/arms) and RM (visits and revisits to never baited holes/arms) errors were calculated for 5 blocks of 10 trials; odd-even reliabilities were determined for the last 20 trials and were shown to be satisfactory for both measures in both types of apparatus. Error-decrements were analyzed by trend components. For both WM and RM, simple and canonical correlations were determined between means and significant trends in maze and holeboard as a test for construct validity; in both experiments r's and Rr's were very low. It was concluded that the concepts WM and RM are not validly generalizable over tests.

摘要

进行了两项实验,以研究空间记忆的两种测量方法,即工作记忆(WM)和参考记忆(RM),是否可以在不同学习情境中通用。在第一个实验中,使用了远交系WU大鼠;在第二个实验中,使用了四个近交系。在两个实验中,大鼠在洞板和高边放射状迷宫中都接受了50次训练试验:16个洞中4个、8个臂中4个放置诱饵。计算了5个包含10次试验的组块中WM(重访有诱饵的洞/臂)和RM(访问和重访从未有诱饵的洞/臂)错误的数量;确定了最后20次试验的奇偶可靠性,结果表明在两种类型的装置中,这两种测量方法的可靠性都令人满意。通过趋势成分分析错误减少情况。对于WM和RM,确定了迷宫和洞板中均值与显著趋势之间的简单和典型相关性,作为对结构效度的检验;在两个实验中,r值和Rr值都非常低。得出的结论是,WM和RM的概念在不同测试中不能有效通用。

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Spatial memory in rats: a cross validation study.大鼠的空间记忆:一项交叉验证研究。
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