Guo Rui, Sakakibara Toshihiko, Mizuno Tetsutaro, Akeda Koji, Kondo Tetsushi, Kasai Yuichi
School of Medicine, Jiangsu University, Zhenjiang, China; Department of Spinal Surgery and Medical Engineering, Mie University Graduate School of Medicine, Tsu City, Mie, Japan.
Department of Spinal Surgery and Medical Engineering, Mie University Graduate School of Medicine, Tsu City, Mie, Japan.
Open Orthop J. 2016 Nov 16;10:539-542. doi: 10.2174/1874325001610010539. eCollection 2016.
It is well-known that many patients will have adverse reactions such as headache and nausea after undergoing myelography, but we have often seen cases where symptoms such as lower back pain and leg pain were alleviated following myelography. To the best of our knowledge, such clinical cases of post-myelographic alleviation have not been reported.
A total of 325 patients with a degenerative lumbar spinal disorder who underwent myelography were prospectively investigated at four hospitals from April 2012 to March 2014 to survey the post-myelographic alleviation of lower back and leg pain prospectively. The severities of lower back pain, leg pain and numbness of the lower extremities were evaluated and intermittent claudication distance was measured before myelography. The magnetic resonance imaging (MRI) findings and myelographic findings were also evaluated for the patients that their symptoms were improved.
Thirty-five of 325 cases (10.8%) of these patients had their symptoms alleviated after undergoing myelography; 26 cases of lower back pain, two cases of leg pain, two cases of numbness of the lower extremity, and five cases of intermittent claudication.
In the patients of a degenerative lumbar spinal disorder, about 10% cases with lower back pain or intermittent claudication had post-myelographic alleviation. Intradural injection therapy might be a therapeutic method to alleviate these symptoms.
众所周知，许多患者在接受脊髓造影后会出现头痛和恶心等不良反应，但我们经常看到脊髓造影后腰痛和腿痛等症状得到缓解的病例。据我们所知，此类脊髓造影后症状缓解的临床病例尚未见报道。
2012年4月至2014年3月，对四家医院共325例患有退行性腰椎疾病并接受脊髓造影的患者进行前瞻性研究，以调查脊髓造影后腰痛和腿痛症状的缓解情况。在脊髓造影前评估腰痛、腿痛和下肢麻木的严重程度，并测量间歇性跛行距离。对症状改善的患者还评估了磁共振成像（MRI）结果和脊髓造影结果。
这些患者中，325例中有35例（10.8%）在接受脊髓造影后症状得到缓解；26例腰痛，2例腿痛，2例下肢麻木，5例间歇性跛行。
在患有退行性腰椎疾病的患者中，约10%的腰痛或间歇性跛行病例在脊髓造影后症状得到缓解。硬膜内注射治疗可能是缓解这些症状的一种治疗方法。
