Charpin D, Vervloet D, Lanteaume A, Kleisbauer J P, Kulling G, Razzouk H, Charpin J
Département des Maladies Respiratoires, Hôpital Sainte-Marguerite, Marseille.
Rev Mal Respir. 1989;6(4):325-8.
To evaluate the role of exposure to furred pets on respiratory allergic disorders, we interviewed 10,338 adults, selected at random from communities of South-East France. All subjects answered a standardized questionnaire related to asthma and perennial rhinitis and to present or past exposure to furred pets and respiratory symptoms related to this exposure. Besides, a sample of the population had a blood analysis for detection of specific IgE directed against common aero-allergens (Phadiatop). Overall, more than half of the households had a pet, more often in rural than urban communities. Among asthmatics 9.3% acknowledged respiratory symptoms when exposed to pets and 5.9% had parted from their pets because of respiratory symptoms; among patients with chronic rhinitis, those figures were 5.1% and 2.6%, respectively. However, these subjects with respiratory symptoms had pets as often as the whole population. In atopic subjects (positive Phadiatop test), exposed to cats, the prevalence of perennial rhinitis was higher than in atopic subjects not exposed to cats and in non-atopic subjects. Thus furred pets have a deleterious influence on patients with asthma or rhinitis, especially in the atopic subgroup. Pet avoidance is an important factor in the management of these diseases.
为评估接触有毛宠物对呼吸道过敏性疾病的作用，我们对从法国东南部社区随机选取的10338名成年人进行了访谈。所有受试者都回答了一份标准化问卷，内容涉及哮喘和常年性鼻炎，以及目前或过去接触有毛宠物的情况和与此接触相关的呼吸道症状。此外，抽取了一部分人群进行血液分析，以检测针对常见空气过敏原的特异性IgE（多价变应原吸附试验）。总体而言，超过半数的家庭养有宠物，农村社区比城市社区更为常见。在哮喘患者中，9.3%的人承认接触宠物时出现呼吸道症状，5.9%的人因呼吸道症状而与宠物分开；在慢性鼻炎患者中，这两个数字分别为5.1%和2.6%。然而，这些有呼吸道症状的受试者养宠物的情况与整个人群一样常见。在特应性受试者（多价变应原吸附试验呈阳性）中，接触猫的人群中常年性鼻炎的患病率高于未接触猫的特应性受试者和非特应性受试者。因此，有毛宠物对哮喘或鼻炎患者有有害影响，尤其是在特应性子组中。避免接触宠物是这些疾病管理中的一个重要因素。
