Mostofa M, McKellar Q A
Department of Veterinary Pharmacology, University of Glasgow, Bearsden.
Res Vet Sci. 1989 Sep;47(2):208-11.
The antimuscarinic drug atropine caused a marked fall in plasma pepsinogen values of sheep with burdens of Ostertagia circumcincta and this response was greater in animals which had higher plasma pepsinogen values before administration of the drug. The response was shown to occur whether the elevated plasma pepsinogen values were a consequence of a larval infection in previously naive or exposed animals or of adult parasites directly transplanted into the abomasum of naive lambs.
抗毒蕈碱药物阿托品可使感染环形奥斯特线虫的绵羊血浆胃蛋白酶原值显著下降，且给药前血浆胃蛋白酶原值较高的动物这种反应更明显。研究表明，无论血浆胃蛋白酶原值升高是先前未感染过寄生虫的动物或已接触过寄生虫的动物因幼虫感染所致，还是直接将成虫寄生虫移植到未感染过寄生虫的羔羊皱胃所致，都会出现这种反应。
