Jenkinson D M, Menzies J D, Pow I A, Inglis L, Lloyd D H, Mackie A
Moredun Research Institute, Edinburgh.
Res Vet Sci. 1989 Sep;47(2):241-6.
Concentrated skin washings, even from vaccinated animals, failed to inhibit the motility of the infective zoospores of Dermatophilus congolensis, or to prevent them from germinating or infecting cattle; their constituent immunoglobulins did not attach to the flagella although IgA and IgG2 did bind to the cell bodies. It is concluded that the specific antibodies at the skin surface of ruminants are unlikely to have a role in zoospore immobilisation. Post vaccination sera rapidly immobilised and clumped the zoospores by means of a coat around the flagella, in which immunoglobulins, particularly IgM, were detected. IgM and IgG1 also attached to the cell bodies of the zoospores.
即使是来自接种过疫苗动物的浓缩皮肤洗液，也无法抑制刚果嗜皮菌感染性游动孢子的运动，或阻止它们发芽或感染牛；其所含的免疫球蛋白虽未附着在鞭毛上，但IgA和IgG2确实与细胞体结合。得出的结论是，反刍动物皮肤表面的特异性抗体不太可能在游动孢子固定中发挥作用。接种疫苗后的血清通过鞭毛周围的一层包膜迅速使游动孢子固定并聚集在一起，在这层包膜中检测到了免疫球蛋白，尤其是IgM。IgM和IgG1也附着在游动孢子的细胞体上。
