Georgiopoulos George, Tsiachris Dimitris, Manolis Antonis S
Third Department of Cardiology, Athens University School of Medicine, Athens, Greece.
Clin Cardiol. 2017 May;40(5):333-342. doi: 10.1002/clc.22653. Epub 2016 Dec 19.
Medical management of atrial fibrillation (AF), the most common arrhythmia in the general population, has had modest efficacy in controlling symptoms and restoring and maintaining sinus rhythm. Since the seminal observation in 1998 that pulmonary veins host the triggers of AF in the majority of cases, electrical isolation of all pulmonary veins constitutes the cornerstone of ablation in patients with symptomatic AF. However, due to the elaborate and tedious technique of the conventional point-by-point method with radiofrequency ablation guided by electroanatomical mapping, newer, more versatile single-shot techniques, such as cryoballoon ablation, have been sought and developed over recent years and are progressively prevailing. Cryoballoon ablation appears to be the most promising practical and effective approach, and we review it here by presenting all available relevant data from the literature as well as from our own experience in an attempt to apprise colleagues of the significant progress made over the last several years in this important field of electrophysiology.
心房颤动（AF）是普通人群中最常见的心律失常，其药物治疗在控制症状以及恢复和维持窦性心律方面效果一般。自1998年首次观察到在大多数情况下肺静脉是房颤的触发部位以来，对所有肺静脉进行电隔离已成为有症状房颤患者消融治疗的基石。然而，由于传统的在电解剖标测引导下逐点进行射频消融的技术复杂且繁琐，近年来人们一直在探索和开发更新的、更通用的单次消融技术，如冷冻球囊消融，并且这种技术正逐渐流行起来。冷冻球囊消融似乎是最有前景的实用且有效的方法，在此我们通过展示来自文献以及我们自身经验的所有可用相关数据对其进行综述，以期让同行了解在这个重要的电生理领域过去几年所取得的重大进展。
