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欧洲疼痛联合会关于慢性疼痛管理中阿片类药物合理使用的立场文件。

European Pain Federation position paper on appropriate opioid use in chronic pain management.

作者信息

O'Brien T, Christrup L L, Drewes A M, Fallon M T, Kress H G, McQuay H J, Mikus G, Morlion B J, Perez-Cajaraville J, Pogatzki-Zahn E, Varrassi G, Wells J C D

机构信息

Marymount University Hospital & Hospice, Curraheen, Cork, Ireland.

Cork University Hospital, Wilton, Cork and College of Medicine and Health, University College, Cork, Ireland.

出版信息

Eur J Pain. 2017 Jan;21(1):3-19. doi: 10.1002/ejp.970.

Abstract

UNLABELLED

Poorly controlled pain is a global public health issue. The personal, familial and societal costs are immeasurable. Only a minority of European patients have access to a comprehensive specialist pain clinic. More commonly the responsibility for chronic pain management and initiating opioid therapy rests with the primary care physician and other non-specialist opioid prescribers. There is much confusing and conflicting information available to non-specialist prescribers regarding opioid therapy and a great deal of unjustified fear is generated. Opioid therapy should only be initiated by competent clinicians as part of a multi-faceted treatment programme in circumstances where more simple measures have failed. Throughout, all patients must be kept under close clinical surveillance. As with any other medical therapy, if the treatment fails to yield the desired results and/or the patient is additionally burdened by an unacceptable level of adverse effects, the overall management strategy must be reviewed and revised. No responsible clinician will wish to pursue a failed treatment strategy or persist with an ineffective and burdensome treatment. In a considered attempt to empower and inform non-specialist opioid prescribers, EFIC convened a European group of experts, drawn from a diverse range of basic science and relevant clinical disciplines, to prepare a position paper on appropriate opioid use in chronic pain. The expert panel reviewed the available literature and harnessed the experience of many years of clinical practice to produce these series of recommendations. Its success will be judged on the extent to which it contributes to an improved pain management experience for chronic pain patients across Europe.

SIGNIFICANCE

This position paper provides expert recommendations for primary care physicians and other non- specialist healthcare professionals in Europe, particularly those who do not have ready access to specialists in pain medicine, on the safe and appropriate use of opioid medications as part of a multi-faceted approach to pain management, in properly selected and supervised patients.

摘要

未标注

疼痛控制不佳是一个全球性的公共卫生问题。其个人、家庭和社会成本难以估量。在欧洲,只有少数患者能够前往综合专科疼痛诊所就诊。更常见的情况是,慢性疼痛管理和启动阿片类药物治疗的责任落在初级保健医生和其他非专科阿片类药物处方医生身上。对于非专科处方医生而言,关于阿片类药物治疗的信息纷繁复杂且相互矛盾,由此产生了大量无端的恐惧。阿片类药物治疗应由有能力的临床医生启动,作为多方面治疗方案的一部分,且仅限于更简单的措施已失效的情况。在整个治疗过程中,所有患者都必须接受密切的临床监测。与任何其他药物治疗一样,如果治疗未能产生预期效果和/或患者因不可接受的不良反应负担过重,则必须对整体管理策略进行审查和修订。没有哪位负责任的临床医生会希望采用失败的治疗策略或坚持无效且负担沉重的治疗方法。为了切实增强非专科阿片类药物处方医生的能力并为其提供信息,欧洲疼痛学会联合会(EFIC)召集了一个由来自不同基础科学和相关临床学科的专家组成的欧洲专家组,编写了一份关于慢性疼痛中阿片类药物合理使用的立场文件。专家小组审查了现有文献,并利用多年临床实践经验制定了这一系列建议。其成功程度将根据它对改善欧洲慢性疼痛患者疼痛管理体验的贡献程度来评判。

意义

本立场文件为欧洲的初级保健医生和其他非专科医疗保健专业人员,特别是那些无法随时获得疼痛医学专家诊治的人员,就作为多方面疼痛管理方法的一部分,在经过适当挑选和监督的患者中安全合理使用阿片类药物提供了专家建议。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e238/6680203/f17d334096cf/EJP-21-3-g001.jpg

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