Bellamy J, Broquie G, Leroy-Terquem E, Verdoux P
Centre chirurgical Val d'Or-Saint-Cloud.
Rev Pneumol Clin. 1989;45(2):86-9.
The authors report the cases of 2 patients who underwent lobectomy followed by irradiation for lung cancer and subsequently developed an aspergillus-infected cavity in the irradiated lung parenchyma. It is far from certain that aspergillosis must always develop in a pre-existing cavity. In cases where it developed on post-radiotherapy lung lesions, our 2 patients and a review of the literature encline us to believe that the fungus itself is responsible for the formation of cavities in lesions of radiation pneumonia. Treatment of such disease can only be surgical, and in spite of post-irradiation and post-surgery sclerosis, elective excision of the lesions is the best solution.
作者报告了2例因肺癌接受肺叶切除术后放疗，随后在放疗后的肺实质中出现曲霉菌感染空洞的病例。曲霉菌病并不一定总是在已有的空洞中发生。在放疗后肺部病变中发生曲霉菌病的病例中，我们的2例患者以及文献回顾使我们倾向于认为真菌本身是放射性肺炎病变中形成空洞的原因。这种疾病的治疗只能是手术治疗，尽管放疗和手术后会出现硬化，但对病变进行选择性切除是最好的解决办法。
