Pratap Himanshu, Dewan R K, Singh L, Gill S, Vaddadi S
Department of Thoracic Surgery, LRS Institute of Tuberculosis and Respiratory Diseases, Mehrauli, New Delhi, India.
Indian J Chest Dis Allied Sci. 2007 Jan-Mar;49(1):23-7.
The objective of this study was to evaluate the immediate and long-term result of resectional surgery in pulmonary aspergilloma.
Seventy-two patients who underwent pulmonary resectional surgery for symptomatic aspergilloma between 1990 to 2002 were studied. Seventy-nine definitive operations were carried out, including one bilateral lobectomy for recurrent lesions and six thoracoplasties to deal with post-operative complications, besides 21 pneumonectomies and 51 lobectomies. There were 10 bilobectomies as well, included in the lobectomy group.
At a mean follow-up of 3.5 years, there were two post-operative deaths and a few complications occurred in 20 cases translating into a morbidity of 28.57% and a mortality of 2.77 percent. Major complications included were persistent air leak, persistent pleural space, empyema, bronchopleural fistula and massive haemorrhage. All events were seen in cases of complex aspergilloma; cases of simple aspergillomas had an uneventful course.
Surgery offers definitive and long-term symptom-free survival in cases of pulmonary aspergilloma at a negligible risk; though almost one-third of those undergoing surgery develop some complications, these are largely manageable.
本研究的目的是评估肺曲菌球切除术的近期和长期效果。
对1990年至2002年间因有症状的曲菌球而接受肺切除术的72例患者进行研究。共进行了79例确定性手术,包括1例因复发病变行双侧肺叶切除术,6例行胸廓成形术以处理术后并发症,此外还有21例全肺切除术和51例肺叶切除术。肺叶切除术组还包括10例双肺叶切除术。
平均随访3.5年,术后有2例死亡,20例出现一些并发症,发病率为28.57%,死亡率为2.77%。主要并发症包括持续性漏气、持续性胸腔、脓胸、支气管胸膜瘘和大量出血。所有这些情况均见于复杂曲菌球病例;单纯曲菌球病例病程平稳。
手术可使肺曲菌球患者获得确定性的长期无症状生存,风险可忽略不计;尽管近三分之一的手术患者会出现一些并发症,但大多可处理。