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光子束剂量学中不同密度探测器横向剂量响应函数的能量依赖性。

The energy dependence of the lateral dose response functions of detectors with various densities in photon-beam dosimetry.

作者信息

Looe Hui Khee, Harder Dietrich, Poppe Björn

机构信息

University Clinic for Medical Radiation Physics, Medical Campus Pius Hospital, Carl von Ossietzky University, Oldenburg, Germany.

出版信息

Phys Med Biol. 2017 Feb 7;62(3):N32-N44. doi: 10.1088/1361-6560/aa54aa. Epub 2016 Dec 19.

Abstract

The lateral dose response function is a general characteristic of the volume effect of a detector used for photon dosimetry in a water phantom. It serves as the convolution kernel transforming the true absorbed dose to water profile, which would be produced within the undisturbed water phantom, into the detector-measured signal profile. The shape of the lateral dose response function characterizes (i) the volume averaging attributable to the detector's size and (ii) the disturbance of the secondary electron field associated with the deviation of the electron density of the detector material from the surrounding water. In previous work, the characteristic dependence of the shape of the lateral dose response function upon the electron density of the detector material was studied for 6 MV photons by Monte Carlo simulation of a wall-less voxel-sized detector (Looe et al 2015 Phys. Med. Biol. 60 6585-07). This study is here continued for Co gamma rays and 15 MV photons in comparison with 6 MV photons. It is found (1) that throughout these photon spectra the shapes of the lateral dose response functions are retaining their characteristic dependence on the detector's electron density, and (2) that their energy-dependent changes are only moderate. This appears as a practical advantage because the lateral dose response function can then be treated as practically invariant across a clinical photon beam in spite of the known changes of the photon spectrum with increasing distance from the beam axis.

摘要

横向剂量响应函数是用于水模体中光子剂量测定的探测器体积效应的一般特征。它作为卷积核,将在未受干扰的水模体中产生的真实水吸收剂量分布转换为探测器测量的信号分布。横向剂量响应函数的形状表征了:(i)由于探测器尺寸导致的体积平均效应,以及(ii)与探测器材料电子密度相对于周围水的偏离相关的二次电子场的扰动。在先前的工作中,通过对无壁体素大小探测器的蒙特卡罗模拟,研究了6兆伏光子情况下横向剂量响应函数形状对探测器材料电子密度的特征依赖性(Looe等人,2015年,《物理医学与生物学》,60卷,6585 - 6607页)。本研究在此继续,将钴γ射线和15兆伏光子与6兆伏光子进行比较。结果发现:(1)在这些光子能谱范围内,横向剂量响应函数的形状保持其对探测器电子密度的特征依赖性;(2)其与能量相关的变化仅为中等程度。这显示出一个实际优势,因为尽管已知光子能谱会随着离射束轴距离的增加而变化,但横向剂量响应函数在临床光子束中仍可被视为基本不变。

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