Looe Hui Khee, Delfs Björn, Poppinga Daniela, Harder Dietrich, Poppe Björn
University Clinic for Medical Radiation Physics, Medical Campus Pius Hospital, Carl von Ossietzky, University, Oldenburg, Germany.
Phys Med Biol. 2017 Jun 21;62(12):5131-5148. doi: 10.1088/1361-6560/aa6ca0. Epub 2017 Apr 11.
The distortion of detector reading profiles across photon beams in the presence of magnetic fields is a developing subject of clinical photon-beam dosimetry. The underlying modification by the Lorentz force of a detector's lateral dose response function-the convolution kernel transforming the true cross-beam dose profile in water into the detector reading profile-is here studied for the first time. The three basic convolution kernels, the photon fluence response function, the dose deposition kernel, and the lateral dose response function, of wall-less cylindrical detectors filled with water of low, normal and enhanced density are shown by Monte Carlo simulation to be distorted in the prevailing direction of the Lorentz force. The asymmetric shape changes of these convolution kernels in a water medium and in magnetic fields of up to 1.5 T are confined to the lower millimetre range, and they depend on the photon beam quality, the magnetic flux density and the detector's density. The impact of this distortion on detector reading profiles is demonstrated using a narrow photon beam profile. For clinical applications it appears as favourable that the magnetic flux density dependent distortion of the lateral dose response function, as far as secondary electron transport is concerned, vanishes in the case of water-equivalent detectors of normal water density. By means of secondary electron history backtracing, the spatial distribution of the photon interactions giving rise either directly to secondary electrons or to scattered photons further downstream producing secondary electrons which contribute to the detector's signal, and their lateral shift due to the Lorentz force is elucidated. Electron history backtracing also serves to illustrate the correct treatment of the influences of the Lorentz force in the EGSnrc Monte Carlo code applied in this study.
在存在磁场的情况下,探测器读数轮廓在光子束中的畸变是临床光子束剂量学中一个正在发展的课题。本文首次研究了洛伦兹力对探测器横向剂量响应函数(即把水中真实的跨束剂量轮廓转换为探测器读数轮廓的卷积核)的潜在修正。通过蒙特卡罗模拟表明,填充有低密度、正常密度和增强密度水的无壁圆柱形探测器的三个基本卷积核,即光子注量响应函数、剂量沉积核和横向剂量响应函数,在洛伦兹力的主导方向上发生畸变。这些卷积核在水介质和高达1.5 T的磁场中的不对称形状变化局限于较低的毫米范围,并且它们取决于光子束质量、磁通密度和探测器密度。利用窄光子束轮廓证明了这种畸变对探测器读数轮廓的影响。对于临床应用而言,就二次电子输运而言,正常水密度的水等效探测器中横向剂量响应函数的磁通密度依赖性畸变消失似乎是有利的。通过二次电子历史回溯,阐明了直接产生二次电子或在下游产生散射光子进而产生对探测器信号有贡献的二次电子的光子相互作用的空间分布,以及它们因洛伦兹力而产生的横向偏移。电子历史回溯还用于说明本研究中应用的EGSnrc蒙特卡罗代码中对洛伦兹力影响的正确处理。