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营养不良患者早期特殊营养支持的益处。

Benefits of early specialized nutritional support in malnourished patients.

作者信息

Morán López Jesús Manuel, Beneítez Moralejo Belén, Piedra León María, Enciso Izquierdo Fidel Jesús, Luengo Pérez Luis Miguel, Amado Señaris José Antonio

机构信息

Unidad de Endocrinología y Nutrición, Complejo Hospitalario de Cáceres, Cáceres, España.

Unidad de Endocrinología y Nutrición, Complejo Hospitalario de Cáceres, Cáceres, España.

出版信息

Med Clin (Barc). 2017 Apr 7;148(7):303-307. doi: 10.1016/j.medcli.2016.10.032. Epub 2016 Dec 16.

DOI:10.1016/j.medcli.2016.10.032
PMID:27993414
Abstract

INTRODUCTION AND OBJECTIVE

Disease related malnutrition (DRM) is highly prevalent in Spain, affecting 23% of in-hospital patients, and is associated with clinical complications. Specialized nutritional support (SNS) can reduce these complications.

MATERIAL AND METHODS

Prospective study carried out in standard clinical practice conditions to test if SNS during the first 5 days of hospitalization, or subsequently, was associated to a lower length of stay or reduced complications in patients with a NRS-2002 score≥3 points.

RESULTS

In the group of patients who initiated early SNS, the length of stay was 8.83 days shorter than in the group with a later introduction (95% CI 3.55-14.10); nevertheless, the higher prevalence of male and oncological patients in this group could have impacted the results. A tendency towards a statistically significant lower mortality rate and a reduced amount of total complications was described.

CONCLUSION

The early introduction of SNS (within the first 5 days of hospitalization) in patients with DRM was associated with a 32.4% reduction in the length of stay.

摘要

引言与目的

疾病相关营养不良(DRM)在西班牙极为普遍,影响着23%的住院患者,且与临床并发症相关。专业营养支持(SNS)可减少这些并发症。

材料与方法

在标准临床实践条件下开展前瞻性研究,以检验住院前5天内或之后进行SNS是否与NRS-2002评分≥3分的患者住院时间缩短或并发症减少相关。

结果

早期开始SNS的患者组住院时间比后期开始SNS的患者组短8.83天(95%置信区间3.55 - 14.10);然而,该组男性和肿瘤患者的较高比例可能影响了结果。研究描述了死亡率在统计学上有显著降低的趋势以及总并发症数量减少的趋势。

结论

DRM患者早期(住院前5天内)引入SNS与住院时间缩短32.4%相关。

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