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Prevalence and severity of malnutrition in hospitalized COVID-19 patients.新冠病毒肺炎住院患者营养不良的患病率及严重程度
Clin Nutr ESPEN. 2020 Dec;40:214-219. doi: 10.1016/j.clnesp.2020.09.018. Epub 2020 Sep 18.
2
Nutritional Risk Screening Tools for Older Adults with COVID-19: A Systematic Review.老年人 COVID-19 患者的营养风险筛查工具:系统评价。
Nutrients. 2020 Sep 27;12(10):2956. doi: 10.3390/nu12102956.
3
Prevalence of malnutrition and analysis of related factors in elderly patients with COVID-19 in Wuhan, China.中国武汉 COVID-19 老年患者营养不良的流行情况及相关因素分析。
Eur J Clin Nutr. 2020 Jun;74(6):871-875. doi: 10.1038/s41430-020-0642-3. Epub 2020 Apr 22.
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A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version).新型冠状病毒(2019-nCoV)感染的肺炎快速诊治指南(标准版)。
Mil Med Res. 2020 Feb 6;7(1):4. doi: 10.1186/s40779-020-0233-6.
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Individualised nutritional support in medical inpatients at nutritional risk: a randomised clinical trial.营养风险的住院患者个体化营养支持:一项随机临床试验。
Lancet. 2019 Jun 8;393(10188):2312-2321. doi: 10.1016/S0140-6736(18)32776-4. Epub 2019 Apr 25.
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Back to the Future: Lessons Learned From the 1918 Influenza Pandemic.重回未来:从 1918 年流感大流行中吸取的教训。
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7
Benefits of early specialized nutritional support in malnourished patients.营养不良患者早期特殊营养支持的益处。
Med Clin (Barc). 2017 Apr 7;148(7):303-307. doi: 10.1016/j.medcli.2016.10.032. Epub 2016 Dec 16.
8
Differences in quality standards when prescribing nutritional support: Differences between specialist and non-specialist physicians.开具营养支持处方时质量标准的差异:专科医生与非专科医生之间的差异。
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新冠病毒中的营养不良与营养支持:营养支持方案的结果。

Malnutrition and nutrition support in COVID-19: The results of a nutrition support protocol.

机构信息

Endocrinology and Nutrition, Hospital Virgen del Puerto (Plasencia), Sociedad Extemeña de Diabetes, Endocrinología y Nutrición, Spain.

出版信息

Endocrinol Diabetes Nutr (Engl Ed). 2021 Nov;68(9):621-627. doi: 10.1016/j.endien.2021.11.019.

DOI:10.1016/j.endien.2021.11.019
PMID:34906342
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8665355/
Abstract

INTRODUCTION

COVID-19 is characterized by various clinical manifestations, mainly respiratory involvement. Disease-related malnutrition is associated with impaired respiratory function and increased all-cause morbidity and mortality. Patients with COVID-19 infection carry a high nutritional risk. After designing a specific nutritional support protocol for this disease, we carried out a retrospective study on malnutrition and on the use of nutritional support in patients with COVID-19.

METHODS

We performed a retrospective study to determine whether nutritional support positively affected hospital stay, clinical complications, and mortality in patients with COVID-19. We compared the results with those of standard nutritional management. Our secondary objectives were to determine the prevalence of malnutrition in patients with COVID-19 and the value of nutritional support in the hospital where the study was performed.

RESULTS

At least 60% of patients with COVID-19 experience malnutrition (up to 78.66% presented at least 1 of the parameters studied). The specialized nutritional support protocol was indicated in only 21 patients (28%) and was started early in only 12 patients (16%). Hospital stay was significantly shorter in patients managed with the early protocol (5.09 days, 95% CI, 1.338-8.853, p<0.01). Similarly, in this group, respiratory distress was less severe and less frequent (41% vs 82.5%, p<0.007), and statistically significantly fewer complications were recorded (9/12 vs 91/63; p<0.001).

CONCLUSIONS

COVID-19 is associated with high rates of disease-related malnutrition. Early implementation of a specialized nutritional support plan can improve the prognosis of these patients by reducing hospital stay, the possibility of more severe respiratory distress, and complications in general.

摘要

简介

COVID-19 的临床特征多种多样,主要为呼吸系统受累。疾病相关的营养不良与呼吸功能受损以及全因发病率和死亡率增加有关。COVID-19 感染患者存在较高的营养风险。在为此病设计特定的营养支持方案后,我们对 COVID-19 患者的营养不良和营养支持的使用情况进行了回顾性研究。

方法

我们进行了一项回顾性研究,以确定营养支持是否对 COVID-19 患者的住院时间、临床并发症和死亡率产生积极影响。我们将结果与标准营养管理进行了比较。我们的次要目标是确定 COVID-19 患者的营养不良患病率以及研究所在医院的营养支持价值。

结果

至少 60%的 COVID-19 患者存在营养不良(高达 78.66%的患者至少存在 1 项研究参数异常)。仅 21 名患者(28%)接受了专门的营养支持方案,只有 12 名患者(16%)早期开始该方案。按照早期方案进行管理的患者住院时间明显缩短(5.09 天,95%置信区间,1.338-8.853,p<0.01)。同样,在该组中,呼吸窘迫的严重程度和频率也较低(41%比 82.5%,p<0.007),且统计上记录的并发症也较少(12 名患者中有 9 例,63 名患者中有 91 例;p<0.001)。

结论

COVID-19 与较高的疾病相关营养不良发生率相关。早期实施专门的营养支持计划可以改善这些患者的预后,缩短住院时间,减少更严重的呼吸窘迫的可能性,并减少一般并发症。