Kim J H, Chu F C, Woodard H Q, Melamed M R, Huvos A, Cantin J
Radiology. 1978 Nov;129(2):501-8. doi: 10.1148/129.2.501.
From the records of Memorial Hospital of the past 50 years, 47 cases with an established diagnosis of radiation-induced sarcoma were identified and divided into two groups: the first included 20 cases of soft-tissue sarcoma arising from irradiated tissues, and the second comprised 27 cases of bone sarcoma arising from normal bones in the irradiated field. Medians for the latent periods from irradiation to diagnosis of bone and soft-tissue sarcoma were 11 and 12, years, respectively. In bone sarcomas, the latent period was longer after larger radiation doses and children appeared to be more susceptible to cancer induction than adults. Criteria for establishing the diagnosis of radiation-induced sarcoma and the magnitude of the risk of bone sarcoma are discussed.
从纪念医院过去50年的记录中，确认了47例已确诊为放射性肉瘤的病例，并将其分为两组：第一组包括20例源自受照射组织的软组织肉瘤，第二组包括27例源自照射野内正常骨骼的骨肉瘤。从照射到诊断骨肉瘤和软组织肉瘤的潜伏期中位数分别为11年和12年。在骨肉瘤中，辐射剂量越大潜伏期越长，儿童似乎比成人更容易诱发癌症。本文讨论了放射性肉瘤的诊断标准以及骨肉瘤的风险程度。
