McCollum Eric D, King Carina, Deula Rashid, Zadutsa Beatiwel, Mankhambo Limangeni, Nambiar Bejoy, Makwenda Charles, Masache Gibson, Lufesi Norman, Mwansambo Charles, Costello Anthony, Colbourn Tim
Department of Pediatrics, Eudowood Division of Pediatric Respiratory Sciences, Johns Hopkins School of Medicine, Rubenstein Building, 200 North Wolfe Street, Baltimore, MD 21287, United States of America .
Institute for Global Health, University College London, London, England .
Bull World Health Organ. 2016 Dec 1;94(12):893-902. doi: 10.2471/BLT.16.173401. Epub 2016 Oct 11.
To investigate implementation of outpatient pulse oximetry among children with pneumonia, in Malawi.
In 2011, 72 health-care providers at 18 rural health centres and 38 community health workers received training in the use of pulse oximetry to measure haemoglobin oxygen saturations. Data collected, between 1 January 2012 and 30 June 2014 by the trained individuals, on children aged 2-59 months with clinically diagnosed pneumonia were analysed.
Of the 14 092 children included in the analysis, 13 266 (94.1%) were successfully checked by oximetry. Among the children with chest indrawing and/or danger signs, those with a measured oxygen saturation below 90% were more than twice as likely to have been referred as those with higher saturations (84.3% [385/457] vs 41.5% [871/2099]; < 0.001). The availability of oximetry appeared to have increased the referral rate for severely hypoxaemic children without chest indrawing or danger signs from 0% to 27.2% ( < 0.001). In the absence of oximetry, if the relevant World Health Organization (WHO) guidelines published in 2014 had been applied, 390/568 (68.7%) severely hypoxaemic children at study health centres and 52/84 (61.9%) severely hypoxaemic children seen by community health workers would have been considered ineligible for referral.
Implementation of pulse oximetry by our trainees substantially increased the referrals of Malawian children with severe hypoxaemic pneumonia. When data from oximetry were excluded, retrospective application of the guidelines published by WHO in 2014 failed to identify a considerable proportion of severely hypoxaemic children eligible only via oximetry.
在马拉维调查肺炎患儿门诊脉搏血氧饱和度测定的实施情况。
2011年,18个农村卫生中心的72名医护人员和38名社区卫生工作者接受了使用脉搏血氧饱和度测定仪测量血红蛋白氧饱和度的培训。对2012年1月1日至2014年6月30日期间由经过培训的人员收集的2至59个月临床诊断为肺炎的儿童的数据进行了分析。
纳入分析的14092名儿童中,13266名(94.1%)成功通过血氧饱和度测定仪进行了检查。在有胸凹陷和/或危险体征的儿童中,测得血氧饱和度低于90%的儿童被转诊的可能性是血氧饱和度较高儿童的两倍多(84.3%[385/457]对41.5%[871/2099];<0.001)。脉搏血氧饱和度测定仪的使用似乎使无胸凹陷或危险体征的严重低氧血症儿童的转诊率从0%提高到了27.2%(<0.001)。在没有脉搏血氧饱和度测定仪的情况下,如果应用2014年世界卫生组织(WHO)发布的相关指南,研究卫生中心390/568(68.7%)的严重低氧血症儿童以及社区卫生工作者诊治的52/84(61.9%)严重低氧血症儿童将被认为不符合转诊条件。
我们的受训人员实施脉搏血氧饱和度测定显著增加了马拉维严重低氧血症肺炎患儿的转诊率。当排除脉搏血氧饱和度测定数据后,回顾性应用WHO 2014年发布的指南未能识别出相当一部分仅通过脉搏血氧饱和度测定仪才能发现的严重低氧血症儿童。