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口腔内浅表性血管瘤的硬化治疗

Sclerotherapy of Intraoral Superficial Hemangioma.

作者信息

Ademi Abdyli Resmije, Abdyli Yll, Perjuci Feriall, Gashi Ali, Agani Zana, Ahmedi Jehona

机构信息

Department of Oral Surgery, Medical Faculty, University of Prishtina, Dental Branch, 10000 Prishtina, Kosovo.

Medical Faculty, University of Prishtina, Dental Branch, 10000 Prishtina, Kosovo.

出版信息

Case Rep Dent. 2016;2016:4320102. doi: 10.1155/2016/4320102. Epub 2016 Nov 23.

DOI:10.1155/2016/4320102
PMID:27994889
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5141317/
Abstract

Hemangioma is the clinical term for a benign vascular neoplasm due to proliferation of the endothelial lining of blood vessels. Their most frequent location is the body skin and oral mucosa. One of the treatment modalities for hemangiomas is intralesional injection of sclerosing agents which cause the damage of blood vessels followed by their obliteration. The objective of the study was to describe the facility of application and evaluate the efficiency of sclerotherapy with aethoxysklerol 1%. . The case presented with intraoral submucosal hemangioma of the cheek was treated by intralesional injection of aethoxysklerol 3% diluted in water for injections at a 4 : 1 ratio (0.75%) at the first appointment and 3 : 1 (1%) at the second appointment. The effect of sclerotherapy was evaluated on the following visits in time intervals of two weeks. . The hemangioma disappeared without complications after the second injection of aethoxysklerol 1%. The successful results of the study were comparable to the data of literature with variations according to the used sclerosant agent, its concentration, the number of injections, and the intervals between each session. . Since sclerotherapy is a very effective, inexpensive, and easy-to-apply treatment, it should be the treatment of choice, especially for intraoral superficial hemangiomas.

摘要

血管瘤是一种因血管内皮细胞增生而形成的良性血管肿瘤的临床术语。其最常见的部位是身体皮肤和口腔黏膜。血管瘤的治疗方法之一是瘤内注射硬化剂,硬化剂会导致血管损伤,随后血管闭塞。本研究的目的是描述1%聚多卡醇硬化疗法的应用便利性并评估其疗效。. 该病例为颊部口腔黏膜下血管瘤,首次就诊时瘤内注射以4∶1比例(0.75%)用水稀释的3%聚多卡醇,第二次就诊时以3∶1比例(1%)注射。在之后每两周的随访中评估硬化疗法的效果。. 第二次注射1%聚多卡醇后,血管瘤消失且无并发症。本研究的成功结果与文献数据相当,但会因所用硬化剂、其浓度、注射次数以及每次治疗之间的间隔而有所不同。. 由于硬化疗法是一种非常有效、廉价且易于应用的治疗方法,它应成为首选治疗方法,尤其是对于口腔内浅表血管瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0be0/5141317/c145f8bc495e/CRID2016-4320102.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0be0/5141317/27a3c1058911/CRID2016-4320102.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0be0/5141317/6211567e6a55/CRID2016-4320102.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0be0/5141317/69f812b5b2cd/CRID2016-4320102.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0be0/5141317/743cb4a59a53/CRID2016-4320102.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0be0/5141317/c145f8bc495e/CRID2016-4320102.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0be0/5141317/27a3c1058911/CRID2016-4320102.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0be0/5141317/6211567e6a55/CRID2016-4320102.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0be0/5141317/69f812b5b2cd/CRID2016-4320102.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0be0/5141317/743cb4a59a53/CRID2016-4320102.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0be0/5141317/c145f8bc495e/CRID2016-4320102.005.jpg

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BMJ Case Rep. 2013 Oct 15;2013:bcr2013200660. doi: 10.1136/bcr-2013-200660.
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Treatment of oral hemangioma with 3% sodium tetradecyl sulfate: study of 20 cases.3%十四烷基硫酸钠治疗口腔血管瘤:20例研究
Indian J Otolaryngol Head Neck Surg. 2012 Sep;64(3):205-7. doi: 10.1007/s12070-011-0249-z. Epub 2011 Apr 13.
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Dent J (Basel). 2022 Nov 9;10(11):214. doi: 10.3390/dj10110214.
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Photobiomodulation associated with sclerotherapy for treatment of hemangioma in the hard palate.光生物调节联合硬化治疗用于治疗硬腭血管瘤。
J Vasc Bras. 2021 Jul 9;20:e20200189. doi: 10.1590/1677-5449.200189. eCollection 2021.
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Examination of oral hemangiomas by intraoral ultrasonography.口腔内超声检查口腔血管瘤。
Oral Radiol. 2021 Oct;37(4):687-692. doi: 10.1007/s11282-021-00511-z. Epub 2021 Mar 3.
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