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[血管畸形(二)。诊断、病理学与治疗]

[Vascular malformations (II). Diagnosis, pathology and treatment].

作者信息

Redondo P

机构信息

Departamento de Dermatología, Clínica Universitaria de Navarra, España.

出版信息

Actas Dermosifiliogr. 2007 May;98(4):219-35.

Abstract

Diagnosis of vascular malformations is essentially clinical, based on the evolution and morphology of lesions. A biopsy is rarely needed to evaluate the nature of the vessels. Imaging examinations are necessary to assess the extension of malformations as well as the osteomuscular and visceral compromise. New techniques such as 3D angio-CT scan and angio-MRI improve the diagnosis of some vascular malformations, especially the large combined ones such as Klippel-Trénaunay syndrome, thus limiting the need for invasive procedures. On the other hand, the advances in laser technology, particularly pulsed dye laser for port-wine stains and Nd:YAG laser for superficial venous malformations constitute new alternatives for the management of these patients. Other emergent treatments include microfoam sclerotherapy for venous and combined, slow-flow malformations, and new embolizing materials associated to surgery for arterio-venous malformations. The second part of this review is focused on the complementary diagnosis (imaging exams, pathology and accessory tests) and multidisciplinary and specific treatment based on the different groups.

摘要

血管畸形的诊断本质上是临床诊断,基于病变的演变和形态。很少需要活检来评估血管的性质。影像学检查对于评估畸形的范围以及骨肌肉和内脏受累情况是必要的。诸如三维血管CT扫描和血管MRI等新技术改善了某些血管畸形的诊断,特别是像克-特综合征这样的大型复合型血管畸形,从而减少了侵入性检查的需求。另一方面,激光技术的进步,特别是用于葡萄酒色斑的脉冲染料激光和用于浅表静脉畸形的Nd:YAG激光,为这些患者的治疗提供了新的选择。其他紧急治疗包括用于静脉和复合型、低流速畸形的微泡沫硬化疗法,以及与动静脉畸形手术相关的新型栓塞材料。本综述的第二部分重点关注辅助诊断(影像学检查、病理学和辅助检查)以及基于不同类型的多学科和特异性治疗。

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