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监测双壳贝类生产区域中软骨藻酸的存在情况。

Monitoring the Presence of Domoic Acid in the Production Areas of Bivalve Molluscs.

作者信息

Rossi Rachele, Arace Olga, Buonomo Maria Giovanna, Capozzo Daniela, Castellano Vincenzo, Imbimbo Samantha, Soprano Vittorio

机构信息

Institute for Experimental Veterinary Medicine of Southern Italy , Portici (NA), Italy.

出版信息

Ital J Food Saf. 2016 Sep 20;5(4):5706. doi: 10.4081/ijfs.2016.5706.

DOI:10.4081/ijfs.2016.5706
PMID:27995097
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5136745/
Abstract

Algal biotoxins, chemical compounds produced by some microscopic algae, constitute the . The mussels, feeding on phytoplankton, can accumulate these compounds to become themselves toxic. There have been several cases of food poisoning by consumption of contaminated shellfish. Such food poisoning have pushed our health care system to provide monitoring of shellfish in the framework of the monitoring plans carried out by AASSLL. In this paper we report the results obtained monitoring the presence of amnesic shellfish poisoning biotoxins, like domoic acid and its isomers, produced by algae. The analyses were carried out by using both the high-performance liquid chromatography-ultraviolet official method and an experimental method performed with a time-of-flight mass spectrometer (ESI-TOF). The 100% of samples analysed by the official method have always been below the limits of sensitivity (except one sample), and the 65% of samples analysed by ESI-TOF showed the presence of domoic acid.

摘要

藻毒素是由一些微藻产生的化合物，构成了……以浮游植物为食的贻贝会积累这些化合物，自身变得有毒。食用受污染贝类导致食物中毒的情况已有多起。此类食物中毒促使我们的医疗保健系统在AASSLL实施的监测计划框架内对贝类进行监测。在本文中，我们报告了监测由藻类产生的失忆性贝类中毒生物毒素（如软骨藻酸及其异构体）的存在情况所获得的结果。分析采用了高效液相色谱 - 紫外官方方法以及使用飞行时间质谱仪（ESI - TOF）进行的实验方法。用官方方法分析的100%的样本（除一个样本外）一直低于灵敏度限值，而用ESI - TOF分析的65%的样本显示存在软骨藻酸。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a42/5136745/be1c2bad8eb7/ijfs-2016-4-5706-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a42/5136745/3989b9ab0e4f/ijfs-2016-4-5706-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a42/5136745/41cd1e1c4ccc/ijfs-2016-4-5706-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a42/5136745/118c8185de26/ijfs-2016-4-5706-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a42/5136745/be1c2bad8eb7/ijfs-2016-4-5706-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a42/5136745/3989b9ab0e4f/ijfs-2016-4-5706-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a42/5136745/41cd1e1c4ccc/ijfs-2016-4-5706-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a42/5136745/118c8185de26/ijfs-2016-4-5706-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a42/5136745/be1c2bad8eb7/ijfs-2016-4-5706-g004.jpg

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本文引用的文献

1
Influences of domoic Acid exposure on cardiac development and the expression of cardiovascular relative genes in zebrafish (Daniorerio) embryos.软骨藻酸暴露对斑马鱼（Danio rerio）胚胎心脏发育及心血管相关基因表达的影响。
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2
Determination of domoic acid in seawater and phytoplankton by liquid chromatography-tandem mass spectrometry.采用液相色谱-串联质谱法测定海水中和浮游植物中的软骨藻酸。
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Developmental toxicity of domoic acid in zebrafish (Danio rerio).
软骨藻酸对斑马鱼（Danio rerio）的发育毒性。
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The amnesic shellfish poisoning mystery.
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