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痣样基底细胞癌综合征——戈林综合征。多发颌骨囊肿与皮肤癌。

The nevoid basal cell carcinoma syndrome--Gorlin's syndrome. Multiple jaw cysts and skin cancer.

作者信息

Gustafson G, Lindahl B, Dahl E, Svensson A

机构信息

Department of Oral Radiology, University of Lund, Sweden.

出版信息

Swed Dent J. 1989;13(4):131-9.

PMID:2799659
Abstract

The nevoid basal cell carcinoma (NBS) syndrome with its characteristic multiple cysts of the jaws and skin cancer is of great interest to the dentist, the dermatologist and the oncologist. The dentist may have the opportunity of making an early diagnosis as the multiple cysts appear mostly in the ramus of the lower jaw. There is a great risk of recurrence as surgical removal is often very complicated. The disease is hereditary and is transmitted through females. The skin cancer can in most cases be treated surgically. It is essential that the family with the syndrome is investigated regularly and at periods of about six months.

摘要

痣样基底细胞癌(NBS)综合征及其特征性的颌骨多发囊肿和皮肤癌,引起了牙医、皮肤科医生和肿瘤学家的极大兴趣。由于多发囊肿大多出现在下颌支,牙医可能有机会做出早期诊断。手术切除往往非常复杂,因此复发风险很大。该疾病具有遗传性,通过女性遗传。在大多数情况下,皮肤癌可以通过手术治疗。对患有该综合征的家庭进行定期(约每六个月)检查至关重要。

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