Neverov N I, Kozlova R I, Vinogradova I V, Galstian G M, Shatskaia O B
Ter Arkh. 1989;61(6):123-6.
A study was made of the content of blood lipids in patients with associated chronic nephritis and arterial hypertension (AH). It has been established that the reduction of arterial pressure as a result of hypotensive therapy (administration of central action drugs, vasodilators of direct action, calcium antagonists, blockers of the angiotensin-transforming enzyme) was followed by a decrease in the blood of the concentration of fatty acids, glycerin, triglycerides, low density lipoproteins, total cholesterol, free cholesterol, phospholipids, characteristics of lipid peroxidation and by the rise of cholesterol concentration in high density lipoproteins. The data obtained are of clinical importance in view of the possibility of correcting dyslipidemia in patients with associated chronic nephritis and arterial hypertension during hypotensive treatment.
对伴有慢性肾炎和动脉高血压(AH)的患者的血脂含量进行了一项研究。已确定,通过降压治疗(使用中枢作用药物、直接作用的血管扩张剂、钙拮抗剂、血管紧张素转换酶阻滞剂)降低动脉血压后,血液中脂肪酸、甘油、甘油三酯、低密度脂蛋白、总胆固醇、游离胆固醇、磷脂的浓度降低,脂质过氧化特征降低,高密度脂蛋白中的胆固醇浓度升高。鉴于在降压治疗期间纠正伴有慢性肾炎和动脉高血压患者的血脂异常的可能性,所获得的数据具有临床重要性。