Yang Wenlei, Zhang Lin
a Department of Ophthalmology , Renji Hospital Affiliated to Medical School, Shanghai Jiaotong University , Shanghai , Shanghai , China.
Curr Eye Res. 2017 May;42(5):655-660. doi: 10.3109/02713683.2016.1167920. Epub 2016 Dec 20.
To investigate the association between corneal temperature on ocular surface and stability of tear film, and define the normal reference range of corneal surface temperature in the population of Pudong New Area, Shanghai, China.
Temperature of cornea (TOC) and tear film break-up time (BUT) were measured among 515 volunteers with or without dry eye. The association between TOC and tear film stability was analyzed, and the normal reference range of TOC was determined.
TOC was 32.6 ± 0.97°C among the 318 subjects without dry eye including 147 males (TOC = 32.6 ± 0.70°C) and 171 females (TOC = 32.64 ± 1.16°C). Significant differences existed in TOC on ocular surface among three separated groups according to BUT measurement. Age was positively related to TOC, whereas BUT was negatively correlated with TOC.
It is recommended to consider 32.6 ± 0.70°C as the normal reference value for human central corneal temperature. Instability of tear film is concomitant with elevated TOC in the population of Pudong New Area, Shanghai.
探讨眼表角膜温度与泪膜稳定性之间的关联，并确定中国上海浦东新区人群角膜表面温度的正常参考范围。
对515名有或无干眼的志愿者测量角膜温度（TOC）和泪膜破裂时间（BUT）。分析TOC与泪膜稳定性之间的关联，并确定TOC的正常参考范围。
在318名无干眼的受试者中，TOC为32.6±0.97°C，其中男性147名（TOC = 32.6±0.70°C），女性171名（TOC = 32.64±1.16°C）。根据BUT测量结果，在三个不同组之间眼表TOC存在显著差异。年龄与TOC呈正相关，而BUT与TOC呈负相关。
建议将32.6±0.70°C作为人类中央角膜温度的正常参考值。在上海浦东新区人群中，泪膜不稳定与TOC升高相伴。
