Chen W M, Zhou Q R, Wang X M, Mao H S, Wang P, Zhou L, Wang W B
Department of Epidemiology, School of Public Health, Fudan University, Key Laboratory of Public Health Safety, Ministry of Education, Collaborative Innovation Center of Social Risks Governance in Health, Shanghai 200032, China.
Center for Disease Control and Prevention of Jiangshan, Jiangshan 324100, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2016 Dec 10;37(12):1683-1686. doi: 10.3760/cma.j.issn.0254-6450.2016.12.024.
Spatial epidemiology and molecular epidemiology have been widely used in the studies of tuberculosis (TB), but each with limitations. Integration of the two methods provides new ideas and methods in TB research. All referenced articles are from CNKI, Wan Fang database, PubMed database and Web of Science database. Method of combining spatial epidemiology and molecular epidemiology has been widely used in determining the local epidemic strains of TB genotype, the transmission mechanism, risk factors of TB, drug-resistant TB, as well as evaluating the effectiveness of TB prevention and control measures. Application of the combined methods is of important significance in the studies of TB, thus worthy to be further introduced to researchers and disease prevention and control workers in this country.