Spangsberg N, Anker-Møller E
Ugeskr Laeger. 1989 Sep 11;151(37):2369-71.
A retrospective investigation was undertaken of the amount of thiopental employed in induction of anaesthesia. This revealed that only three factors were of significance for the dosage employed: age, weight and cardiac disease. In patients over the age of 70 years, the dosage could be reduced by 30%. In patients of more than 10% overweight, the dosage could be reduced by 7% and in patients who were 10% underweight, the dosage was increased by 10%. In cases of heart disease the dosage was reduced by 20% in the proportion of 5 mg thiopental per kg body-weight.
对麻醉诱导中使用的硫喷妥钠用量进行了回顾性调查。结果显示，对于所使用的剂量，只有三个因素具有重要意义：年龄、体重和心脏病。70岁以上的患者，剂量可减少30%。体重超重超过10%的患者，剂量可减少7%，体重低于标准体重10%的患者，剂量增加10%。对于患有心脏病的患者，每公斤体重5毫克硫喷妥钠的剂量比例减少20%。
