血流限制对阻力运动反应中肌生成生物标志物的影响。
Effects of blood-flow restriction on biomarkers of myogenesis in response to resistance exercise.
作者信息
Layne Andrew S, Larkin-Kaiser Kelly, MacNeil R Gavin, Dirain Marvin, Sandesara Bhanuprasad, Manini Todd M, Buford Thomas W
机构信息
a University of Florida, 2004 Mowry Rd. Gainesville, FL 32611, USA.
b University of Calgary, 2500 University Drive NW. Calgary, AB T2N 1N4, Canada.
出版信息
Appl Physiol Nutr Metab. 2017 Jan;42(1):89-92. doi: 10.1139/apnm-2016-0224. Epub 2016 Oct 18.
Abstract
We investigated the acute myogenic response to resistance exercise with and without blood-flow restriction (BFR). Six men and women (age, 22 ± 1 years) performed unilateral knee extensions at 40% of 1-repetition maximum with or without (CNTRL) BFR applied via pressure cuff inflated to 220 mm Hg. Muscle biopsies were collected at 4 h and 24 h postexercise. Addition of BFR increased myoD and c-Met messenger RNA expression relative to CNTRL. Expression of hepatocyte growth factor protein was significantly higher following CNTRL.
摘要
我们研究了有无血流限制（BFR）情况下抗阻运动的急性肌源性反应。六名男性和女性（年龄22±1岁）在1次重复最大值的40%下进行单侧膝关节伸展，施加或不施加（对照组）通过充气至220毫米汞柱的压力袖带进行的BFR。在运动后4小时和24小时采集肌肉活检样本。与对照组相比，添加BFR增加了肌分化抗原（myoD）和肝细胞生长因子受体（c-Met）信使核糖核酸（mRNA）的表达。对照组后肝细胞生长因子蛋白的表达显著更高。
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