Tomasian Anderanik, Wallace Adam N, Hillen Travis J, Jennings Jack W
Department of Radiology, Musculoskeletal Division, University of Southern California, Los Angeles, California.
Mallinckrodt Institute of Radiology, Neuroradiology Section, Washington University School of Medicine, Saint Louis, Missouri.
Semin Musculoskelet Radiol. 2016 Nov;20(5):472-485. doi: 10.1055/s-0036-1594281. Epub 2016 Dec 21.
Percutaneous image-guided ablation has been shown to be safe and effective for the treatment of benign osseous lesions and has evolved into the treatment of metastatic lesions for both pain palliation and local tumor control. Ablation is increasingly becoming part of the treatment algorithm of painful bone lesions, requiring multidisciplinary input from radiation, surgical, and medical oncologists. Substantial pain reduction is often possible in those who have failed to benefit from conventional therapies such as systemic and radiation therapy. This review details the basics of bone ablation including indications, treatment algorithms, ablation modalities, role of imaging, thermo-protective techniques, and the emerging use for local tumor control in patients with oligometastatic disease.
经皮影像引导下消融已被证明对良性骨病变的治疗是安全有效的,并且已发展到用于转移性病变的治疗,以缓解疼痛和进行局部肿瘤控制。消融越来越成为疼痛性骨病变治疗方案的一部分,这需要放射肿瘤学家、外科肿瘤学家和内科肿瘤学家的多学科参与。对于那些未能从全身治疗和放射治疗等传统疗法中获益的患者,通常有可能大幅减轻疼痛。本综述详细介绍了骨消融的基础知识,包括适应症、治疗方案、消融方式、成像的作用、热保护技术以及寡转移疾病患者局部肿瘤控制的新应用。