Holbert John A, Nguyen Dan T
College of Medicine, Penn State University College of Medicine.
Interventional Neuroradiology, Penn State Hershey Medical Center, Hershey, USA.
Cureus. 2018 May 4;10(5):e2579. doi: 10.7759/cureus.2579.
Percutaneous image-guided ablation is used for treatment of both benign and malignant osseous lesions often leading to substantial pain relief and local tumor control. Paired with vertebral augmentation of the affected vertebra, patients can often become functional and experience significant pain reduction. However, bone ablation must be paired with various modalities of treatment as it only provides pain relief and local tumor control and does not address systemic metastatic disease. We describe a case of metastatic prostate cancer with epidural extension treated with percutaneous image-guided radiofrequency ablation and vertebral augmentation leading to substantial pain relief as well as resolution of the epidural disease as evidenced by short-term follow-up magnetic resonance imaging (MRI). To the best of our knowledge, the resolution of epidural disease has not been described before. This case highlights the potential of ablative therapy in metastatic bone disease, particularly in the presence of epidural disease.
经皮影像引导下消融术用于治疗良性和恶性骨病变,通常可显著缓解疼痛并实现局部肿瘤控制。与受影响椎体的椎体强化术相结合,患者通常能够恢复功能并经历疼痛显著减轻。然而,骨消融必须与各种治疗方式相结合,因为它仅能缓解疼痛和实现局部肿瘤控制,无法解决系统性转移性疾病。我们描述了一例伴有硬膜外扩展的转移性前列腺癌病例,该病例接受了经皮影像引导下射频消融和椎体强化治疗,短期随访磁共振成像(MRI)显示疼痛显著缓解且硬膜外疾病消退。据我们所知,此前尚未有硬膜外疾病消退的相关报道。该病例凸显了消融治疗在转移性骨病中的潜力,尤其是在存在硬膜外疾病的情况下。