Ainoda Yusuke, Takeshita Nozomi, Hase Ryota, Mikawa Takahiro, Hosokawa Naoto, Kawamura Ichiro, Kurai Hanako, Abe Masahiro, Kimura Muneyoshi, Araoka Hideki, Fujita Takahiro, Totsuka Kyoichi, Mezaki Kazuhisa, Sekiya Noritaka, Ohmagari Norio
Disease Control and Prevention Center, National Center for Global Health and Medicine.
Department of Infectious Diseases, Tokyo Metropolitan Health and Medical Corporation Ebara Hospital.
Jpn J Infect Dis. 2017 Jul 24;70(4):405-407. doi: 10.7883/yoken.JJID.2016.130. Epub 2016 Dec 22.
Staphylococcus lugdunensis (SL) is a bacterium with a highly pathogenicity than most other coagulase-negative Staphylococcus spp. (CoNS). In Japan, data on this pathogen are sparse, and the current prevalence of SL bacteremia is unknown. Therefore, we investigated the prevalence of SL in blood culture specimens in a prospective multicenter study across 5 facilities. A total of 3,284 patients had positive blood cultures, and 2,478 patients had bacteremia. Among the patients with bacteremia, 7 patients (0.28%) had SL bacteremia. A total of 281 patients had CoNS bacteremia, with SL accounting for 2.49% of these cases. Of the 7 patients with SL bacteremia, 1 patient (14.3%) had infective endocarditis, and 1 patient (14.3%) died within 30 days. In this study, SL resulted in the development of bacteremia in select patients. Clinicians in Japan should be aware of the prevalence of SL and the complications of SL bacteremia.
路邓葡萄球菌（SL）是一种致病性高于大多数其他凝固酶阴性葡萄球菌属（CoNS）细菌的细菌。在日本，关于这种病原体的数据很少，目前SL菌血症的流行情况尚不清楚。因此，我们在一项跨越5个机构的前瞻性多中心研究中调查了血培养标本中SL的流行情况。共有3284例患者血培养呈阳性，2478例患者发生菌血症。在菌血症患者中，7例（0.28%）发生了SL菌血症。共有281例患者发生CoNS菌血症，其中SL占这些病例的2.49%。在7例SL菌血症患者中，1例（14.3%）患有感染性心内膜炎，1例（14.3%）在30天内死亡。在本研究中，SL导致部分患者发生菌血症。日本的临床医生应了解SL的流行情况以及SL菌血症的并发症。
