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[高压氧疗对肿瘤生长的影响]

[Effects of hyperbaric oxygenation on tumor growth].

作者信息

Frid I A, Sapov I A, Katyshev A V, Lupanov A I, Rudakov V F, Semiachkina S O, Shul'ga N I

出版信息

Vopr Onkol. 1989;35(8):970-3.

PMID:2800446
Abstract

The study failed to show a stimulating effect of hyperbaric oxygen on growth and metastatic spreading of sarcoma 37 transplanted subcutaneously or intravenously to female SHR mice, melanoma B16 intramuscularly transplanted to female C57/Bl mice and methylcholanthrene-induced tumors in female albino noninbred rats. An insignificant inhibitory effect of hyperbaric oxygen on transplantable tumor growth and development of inducible ones in experimental animals was observed.

摘要

该研究未能表明高压氧对皮下或静脉移植到雌性SHR小鼠的肉瘤37、肌肉注射移植到雌性C57/Bl小鼠的黑色素瘤B16以及雌性白化非近交大鼠中甲基胆蒽诱导肿瘤的生长和转移扩散有刺激作用。观察到高压氧对实验动物中可移植肿瘤的生长以及诱导性肿瘤的发展有不显著的抑制作用。

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