[急性脑膜炎患者脑脊液中的肌酸磷酸激酶]
[Creatine phosphokinase in the cerebrospinal fluid of patients with acute meningitis].
作者信息
Smirnov V V, Skorniakov V I, Popov A S, Shestakova T I, Khot'ko L P
出版信息
Vrach Delo. 1989 Jul(7):112-3.
PMID:2800482
Abstract
A study is presented of the general activity and isoenzymatic spectrum of creatine phosphokinase (CPK) in the cerebrospinal fluid (CSF) in patients with acute meningitis of different etiology. The enzymatic activity proved to be increased due to the cerebral (CPK-BB) isoform. Liberation of CPK-BB from the brain tissue and its penetration into the intercellular fluid and then into the CSF was related to the functional-structural changes in the cellular membranes of the brain in meningitis.
摘要
本文呈现了一项关于不同病因的急性脑膜炎患者脑脊液（CSF）中肌酸磷酸激酶（CPK）的总体活性及同工酶谱的研究。酶活性被证明因脑型（CPK-BB）同工型而升高。CPK-BB从脑组织的释放及其渗透到细胞间液进而进入脑脊液与脑膜炎时脑细胞膜的功能结构变化有关。
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