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[从东北亚地区蚊虫中分离出加利福尼亚脑炎和本扬韦拉病毒抗原复合物的病毒(布尼亚病毒科,布尼亚病毒属)]

[Isolation of viruses of antigenic complexes of California encephalitis and Bunyamwera (Bunyaviridae, Bunuavirus) from mosquitoes in northeast Asia].

作者信息

L'vov S D, Gromashevskiĭ V L, Voropanov Iu V, Andreev V P, Skvortsova T M

出版信息

Vopr Virusol. 1989 May-Jun;34(3):333-8.

PMID:2800529
Abstract

Studies in suckling mice and by direct solid-phase enzyme immunoassay were carried out with 111,1 thousand Aedes mosquitoes collected in July, 1986, in tundra, forest-tundra, and northern taiga of Kamchatka region and Chukotka autonomous district of Magadan region (North-Pacific natural area within 69 degrees-53 degrees North and 156 degrees-177 degrees East). Eleven strains were isolated of which 7 were classified as members of the California encephalitis complex (Tahyna-like strains) and 4 as members of the Bunyamwera complex (Batai-like strains). According to electron-microscopic studies of 2 strains (one from each antigenic complex), both were classified as belonging to the family of Bunyaviridae. Strains of both complexes were isolated in all landscape zones examined--tundra, forest-tundra, northern taiga. Virus-neutralizing antibodies to them were found in human and reindeer sera also in all the landscape zones, to Tahyna virus in 11%-61%, to Batain virus in 2%-6% blood specimens. No antibody to Uukuniemi virus was found.

摘要

对1986年7月在堪察加半岛地区以及马加丹州楚科奇自治区(北纬69度至53度、东经156度至177度之间的北太平洋自然区域)的苔原、森林苔原和北部泰加林地带采集的11.1万只伊蚊进行了乳鼠研究和直接固相酶免疫测定。分离出了11株病毒,其中7株被归类为加利福尼亚脑炎病毒群成员(类塔希纳病毒株),4株被归类为布尼亚姆韦拉病毒群成员(类巴泰病毒株)。根据对2株病毒(每种抗原复合物各1株)的电子显微镜研究,二者均被归类为布尼亚病毒科。在所有检测的景观区域——苔原、森林苔原、北部泰加林——均分离出了这两种病毒群的毒株。在所有景观区域的人类和驯鹿血清中也发现了针对它们的病毒中和抗体,在11% - 61%的血液样本中发现了针对塔希纳病毒的抗体,在2% - 6%的血液样本中发现了针对巴泰因病毒的抗体。未发现针对乌昆耶米病毒的抗体。

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