[俄罗斯北部地区加利福尼亚脑炎血清群病毒（布尼亚病毒科，布尼亚病毒属）的分布情况]

[Distribution of viruses from the Californian encephalitis serogroup (Bunyaviridae, Bunyavirus) in the northern expanses of Russia].

作者信息

L'vov S D, Gromashevskiĭ V L, Morozova T N, Aristova V A, Skvortsova T M, Galkina I V, L'vov D K, Butenko A M, Mitchell K D, Savage H M, Selivanov Ia M, Egorov N Ia, Androsov I A, Tugutov L D, Cherniavskiĭ V F, Mikhaĭlova N B, Mayer V A, Galimov V R, Sokolova N G, Andronova O N, Semenov V B, Baĭluk F N, Pogorelyĭ Iu D, Fadeev E S, Grekov E I

出版信息

Vopr Virusol. 1997 Sep-Oct;42(5):229-35.

PMID:9424850

Abstract

The study was carried out in 1983-1991 and covered a territory of about 10 x 10(6) km2 in various physico-geographic areas (East Fennoscandia, Northern Russian Plain, West Siberia, Central Siberia, North-Eastern Siberia, and Northern Pacific Region) in the Arctic, Subarctic, Northern-Central-Southern taiga, forest-steppe, and steppe in Northern Russia. A total of 251 strains were isolated from 1391,900 mosquitoes, identified as the California group snowshoe hare (83), Inkoo (44), and Tahyna (2) viruses; 122 strains were not completely identified. Some of the strains with uncommon antigenic composition can be natural reassortants. Fifty-two percent of strains were isolated from Aedes communis and the associate species of mosquitoes, other hosts were A. excrucians (8%), A. cantans (6.25%), A. flavescens (6.25%), A. ciprius (6.25%), A. punctor (4.5%), A. vexans (4.5%), A. cataphylla (3.6%), A. nigripes (3.6%), and A. hexodontus (2.6%). The infection rate of mosquitoes was 0.009% in the tundra, 0.012% in forest-tundra, 0.01% in Northern taiga, 0.02% in Central taiga, 0.017% in Southern taiga, 0.026% in forest-steppe, and 0.097% in steppe. The epidemic season is one month in the tundra (from the beginning of July till the beginning of August), two months in Northern taiga (July-August), and three months in Central taiga (from the second half of June till the beginning of September). The highest infection rate of mosquitoes was observed at the end of the epidemic season in all regions. SSH strains prevailed to the East from the Enisei river, whereas to the West and in the Subarctic regions INK virus predominated, SSH being rare; in the taiga the distribution was quite the opposite. TAH virus was virtually absent. Human morbidity was observed in all territories studied. The immune stratum of adult population is about 30% in the tundra and forest-tundra and about 50% in Northern and Central taiga.

摘要

该研究于1983年至1991年开展，覆盖了北极、亚北极、北-中-南泰加林、森林草原和俄罗斯北部草原等不同自然地理区域（东芬诺斯坎迪亚、俄罗斯北部平原、西西伯利亚、中西伯利亚、东北西伯利亚和北太平洋地区）约10×10⁶平方千米的地域。从1391900只蚊子中总共分离出251株病毒，鉴定为加利福尼亚组雪鞋兔病毒（83株）、因库奥病毒（44株）和塔希纳病毒（2株）；122株未完全鉴定。一些具有不寻常抗原组成的毒株可能是自然重配体。52%的毒株是从普通伊蚊及其相关蚊种中分离出来的，其他宿主有严酷伊蚊（8%）、刺扰伊蚊（6.25%）、黄色伊蚊（6.25%）、塞浦路斯伊蚊（6.25%）、凶小库蚊（4.5%）、骚扰伊蚊（4.5%）、叶状伊蚊（3.6%）、黑足伊蚊（3.6%）和六齿伊蚊（2.6%）。蚊子的感染率在苔原带为0.009%，森林苔原带为0.012%，北泰加林为0.01%，中泰加林为0.02%，南泰加林为0.017%，森林草原为0.026%，草原为0.097%。流行季节在苔原带为1个月（从7月初到8月初），北泰加林为2个月（7月至8月），中泰加林为3个月（从6月下旬到9月初）。在所有地区，蚊子的最高感染率出现在流行季节末期。在叶尼塞河以东，雪鞋兔病毒毒株占主导，而在叶尼塞河以西和亚北极地区，因库奥病毒占主导，雪鞋兔病毒罕见；在泰加林地区，分布情况则相反。塔希纳病毒几乎不存在。在所有研究地区均观察到人类发病情况。成年人群的免疫水平在苔原带和森林苔原带约为30%，在北泰加林和中泰加林约为50%。