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[Effect of procaine and procaine metabolites on coenzyme A and acetyl coenzyme A concentration in various tissues of the rat].

作者信息

Kietzmann M, Kaemmerer K

机构信息

Institut für Pharmakologie, Toxikologie und Pharmazie, Tierärztliche Hochschule Hannover.

出版信息

Z Alternsforsch. 1989 Jul-Aug;44(4):211-7.

PMID:2800573
Abstract

In rats treated with procaine hydrochloride, diethylaminoethanol, monoethylaminoethanol, ethanolamine, as well as a combination of procaine hydrochloride and haematoporphyrine the ratio of acetyl coenzyme A and coenzyme A clearly was enhanced in the liver and to a minor extent in the cerebellum. In the tissue of cerebral cortex, heart, muscle and duodenum no corresponding effects were demonstrated. These findings, showing a further intermediary effect of orally administered procaine, can be interpreted as an influence in intermediary energy utilisation.

摘要

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