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高压氧疗法预防填充剂注射致盲

Hyperbaric Oxygen Therapy to Avoid Blindness From Filler Injection.

作者信息

Hwang Kun

机构信息

Department of Plastic Surgery, Inha University School of Medicine, Incheon, Korea.

出版信息

J Craniofac Surg. 2016 Nov;27(8):2154-2155. doi: 10.1097/SCS.0000000000003089.

DOI:10.1097/SCS.0000000000003089
PMID:28005776
Abstract

The most serious complication of filler or fat injection is blindness. According to a recent systematic review of 98 patients of blindness provoked by filler or fat injection, only 2 patients had the outcome of a complete recovery of vision.In the literature, only 2 papers were found in which hyperbaric oxygen therapy (HBOT) was used in ophthalmic artery obstruction. However, no improvement of vision was obtained in either patient. Recently, the authors treated a patient who had central retinal vein occlusion and cilioretinal artery occlusion with HBOT (daily 2-hour sessions at 253 kPa for 14 days), and his visual acuity returned to normal.In central retinal artery obstruction, if the cilioretinal artery is present, it will maintain the thickness of the retina to a variable extent. Though the size of the cilioretinal artery and the area it supplies varies, 36.2% (32.1-40.2%) of people have a cilioretinal artery.Thereafter, HBOT might be applied to patients with central retinal artery occlusion following filler injection.

摘要

填充剂或脂肪注射最严重的并发症是失明。根据最近一项对98例因填充剂或脂肪注射引发失明患者的系统评价,仅有2例患者视力完全恢复。在文献中,仅发现2篇关于在眼动脉阻塞中使用高压氧疗法(HBOT)的论文。然而,这2例患者的视力均未得到改善。最近,作者用HBOT(在253 kPa下每日治疗2小时,共14天)治疗了1例患有视网膜中央静脉阻塞和睫状视网膜动脉阻塞的患者,其视力恢复正常。在视网膜中央动脉阻塞中,如果存在睫状视网膜动脉,它会在不同程度上维持视网膜厚度。尽管睫状视网膜动脉的大小及其供血面积各不相同,但36.2%(32.1 - 40.2%)的人有睫状视网膜动脉。此后,HBOT可能适用于填充剂注射后发生视网膜中央动脉阻塞的患者。

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Am J Ophthalmol Case Rep. 2024 Dec 3;36:102229. doi: 10.1016/j.ajoc.2024.102229. eCollection 2024 Dec.
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Adverse Effects Associated with Dermal Filler Treatments: Part II Vascular Complication.与真皮填充剂治疗相关的不良反应:第二部分 血管并发症
Diagnostics (Basel). 2024 Jul 18;14(14):1555. doi: 10.3390/diagnostics14141555.
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Role of Hyperbaric Oxygen in Filler-Induced Vascular Occlusion.
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Aesthetic Plast Surg. 2024 Jul;48(14):2713-2721. doi: 10.1007/s00266-024-03920-7. Epub 2024 Mar 8.
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Clinical Manifestations and Prognosis of Embolism Caused by Filler Injection in Different Facial Regions.不同面部区域填充剂注射所致栓塞的临床表现及预后
Plast Reconstr Surg Glob Open. 2023 Aug 29;11(8):e5225. doi: 10.1097/GOX.0000000000005225. eCollection 2023 Aug.
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Oxygen therapy in patients with retinal artery occlusion: A meta-analysis.视网膜动脉阻塞患者的氧疗:一项荟萃分析。
PLoS One. 2018 Aug 29;13(8):e0202154. doi: 10.1371/journal.pone.0202154. eCollection 2018.