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不同面部区域填充剂注射所致栓塞的临床表现及预后

Clinical Manifestations and Prognosis of Embolism Caused by Filler Injection in Different Facial Regions.

作者信息

Zhuang Jun, Zheng Qiaoyuan, Su Xueshang, Jiang Liya, Hu Jintian

机构信息

From the Department of Ear Reconstruction, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

College of Clinical Medicine, Fudan University, Xuhui District, Shanghai, China.

出版信息

Plast Reconstr Surg Glob Open. 2023 Aug 29;11(8):e5225. doi: 10.1097/GOX.0000000000005225. eCollection 2023 Aug.

DOI:10.1097/GOX.0000000000005225
PMID:37650096
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10465098/
Abstract

BACKGROUND

Embolism is a serious complication after facial filling, with a usually poor prognosis of the symptoms after embolism. The authors systematically reviewed reported cases of facial vascular embolism, explored the relationship between the location and material used for facial filling and occurrence of vascular embolism, and assessed the prognosis of complications after vascular embolism.

METHODS

This study provides a systematic review of published cases of vascular embolism after facial filling. A summary of the filling materials and filling sites for each case, the adverse reactions and embolized blood vessels, a recording of the time when each patient experienced adverse reactions and started treatment, and a presentation of their prognosis are provided.

RESULTS

The frontal, eyebrow, and nose are common filling sites causing facial embolism. The main clinical manifestations after embolism were visual impairment, skin necrosis, and ptosis. The prognosis of visual impairment after embolization was poor, whereas skin necrosis and ptosis generally improved after treatment.

CONCLUSIONS

This article aimed to review the clinical manifestations, therapies, and prognosis of embolism after facial filling. A better understanding of these complications can help clinicians to detect the occurrence of complications as early as possible and give patients timely treatment.

摘要

背景

栓塞是面部填充术后的一种严重并发症,栓塞后症状的预后通常较差。作者系统回顾了已报道的面部血管栓塞病例,探讨了面部填充的部位和所用材料与血管栓塞发生之间的关系,并评估了血管栓塞后并发症的预后。

方法

本研究对已发表的面部填充后血管栓塞病例进行系统回顾。提供了每个病例的填充材料和填充部位总结、不良反应和栓塞血管情况、每位患者出现不良反应及开始治疗的时间记录以及其预后情况。

结果

额部、眉部和鼻部是导致面部栓塞的常见填充部位。栓塞后的主要临床表现为视力障碍、皮肤坏死和上睑下垂。栓塞后视力障碍的预后较差,而皮肤坏死和上睑下垂经治疗后一般有所改善。

结论

本文旨在回顾面部填充后栓塞的临床表现、治疗方法及预后。更好地了解这些并发症有助于临床医生尽早发现并发症的发生并及时给予患者治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6508/10465098/720907c207e4/gox-11-e5225-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6508/10465098/0dae38d9dfae/gox-11-e5225-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6508/10465098/720907c207e4/gox-11-e5225-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6508/10465098/0dae38d9dfae/gox-11-e5225-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6508/10465098/720907c207e4/gox-11-e5225-g002.jpg

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Administration Method and Potential Efficacy of Hyaluronidase for Hyaluronic Acid Filler-Related Vision Loss: A Systematic Review.透明质酸酶治疗透明质酸填充剂相关视力丧失的给药方法和潜在疗效:系统评价。
Aesthetic Plast Surg. 2024 Feb;48(4):709-718. doi: 10.1007/s00266-022-03215-9. Epub 2022 Dec 27.
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Long-term Prognosis of Vision Loss Caused by Facial Hyaluronic Acid Injections and the Potential Approaches to Address This Catastrophic Event.
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Gels. 2024 Aug 12;10(8):530. doi: 10.3390/gels10080530.
面部透明质酸注射所致视力丧失的长期预后及应对这一灾难性事件的潜在方法。
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