Trappe H J, Brugada P, Talajic M, Lezaun R, Wellens H J
Abreilung Kardiologie des Akademischen Krankenhauses Maastricht, Holland.
Z Kardiol. 1989 Aug;78(8):500-9.
We studied the follow-up of 49 patients (pts), mean age 34 +/- 9 years, without coronary artery disease who had sustained (duration greater than 30 s) monomorphic ventricular tachycardia (smvt) (n = 42) or ventricular fibrillation (vf) (n = 7). There were 9/49 pts (18%) with smvt who had right ventricular dysplasia (RVD) and 32/49 pts (65%) without structural heart disease ("idiopathic" ventricular arrhythmia) (26/32 pts with smvt and 6/32 pts with vf). There were 6/49 pts (12%) with congestive (COCM) and 2/49 pts (4%) with hypertrophic (HOCM) cardiomyopathy. Mean follow-up was 49 +/- 13 months. During the follow-up 1/9 pts (11%) with RVD died postoperatively from heart failure, 1/26 pts (4%) with idiopathic smvt from cancer and 2/6 pts (33%) with COCM from heart failure. There were no deaths in pts with idiopathic vf. Recurrent smvt occurred in 5/9 pts (56%) with RVD, in 10/26 pts (39%) with idiopathic smvt, in 2/6 pts (33%) with idiopathic vf, in 3/6 pts (50%) with COCM and in 1/2 pts (50%) with HOCM. Our data show that pts with smvt or vf without coronary artery disease have a good prognosis. However, there is a high incidence of recurrent ventricular arrhythmia in these patients.
我们研究了49例患者，平均年龄34±9岁，无冠心病，曾发生持续性（持续时间大于30秒）单形性室性心动过速（smvt）（n = 42）或心室颤动（vf）（n = 7）。49例患者中有9例（18%）smvt患者患有右心室发育不良（RVD），32例（65%）无结构性心脏病（“特发性”室性心律失常）（smvt患者26例，vf患者6例）。49例患者中有6例（12%）患有充血性心肌病（COCM），2例（4%）患有肥厚性心肌病（HOCM）。平均随访时间为49±13个月。随访期间，1例（11%）RVD患者术后死于心力衰竭，1例（4%）特发性smvt患者死于癌症，2例（33%）COCM患者死于心力衰竭。特发性vf患者无死亡病例。复发性smvt发生在5例（56%）RVD患者、10例（39%）特发性smvt患者、2例（33%）特发性vf患者、3例（50%）COCM患者和1例（50%）HOCM患者中。我们的数据表明，无冠心病的smvt或vf患者预后良好。然而，这些患者室性心律失常复发的发生率很高。
