Trappe H J, Brugada P, Talajic M, Lezaun R, Wellens H J
Abreilung Kardiologie des Akademischen Krankenhauses Maastricht, Holland.
Z Kardiol. 1989 Aug;78(8):500-9.
We studied the follow-up of 49 patients (pts), mean age 34 +/- 9 years, without coronary artery disease who had sustained (duration greater than 30 s) monomorphic ventricular tachycardia (smvt) (n = 42) or ventricular fibrillation (vf) (n = 7). There were 9/49 pts (18%) with smvt who had right ventricular dysplasia (RVD) and 32/49 pts (65%) without structural heart disease ("idiopathic" ventricular arrhythmia) (26/32 pts with smvt and 6/32 pts with vf). There were 6/49 pts (12%) with congestive (COCM) and 2/49 pts (4%) with hypertrophic (HOCM) cardiomyopathy. Mean follow-up was 49 +/- 13 months. During the follow-up 1/9 pts (11%) with RVD died postoperatively from heart failure, 1/26 pts (4%) with idiopathic smvt from cancer and 2/6 pts (33%) with COCM from heart failure. There were no deaths in pts with idiopathic vf. Recurrent smvt occurred in 5/9 pts (56%) with RVD, in 10/26 pts (39%) with idiopathic smvt, in 2/6 pts (33%) with idiopathic vf, in 3/6 pts (50%) with COCM and in 1/2 pts (50%) with HOCM. Our data show that pts with smvt or vf without coronary artery disease have a good prognosis. However, there is a high incidence of recurrent ventricular arrhythmia in these patients.
我们研究了49例患者,平均年龄34±9岁,无冠心病,曾发生持续性(持续时间大于30秒)单形性室性心动过速(smvt)(n = 42)或心室颤动(vf)(n = 7)。49例患者中有9例(18%)smvt患者患有右心室发育不良(RVD),32例(65%)无结构性心脏病(“特发性”室性心律失常)(smvt患者26例,vf患者6例)。49例患者中有6例(12%)患有充血性心肌病(COCM),2例(4%)患有肥厚性心肌病(HOCM)。平均随访时间为49±13个月。随访期间,1例(11%)RVD患者术后死于心力衰竭,1例(4%)特发性smvt患者死于癌症,2例(33%)COCM患者死于心力衰竭。特发性vf患者无死亡病例。复发性smvt发生在5例(56%)RVD患者、10例(39%)特发性smvt患者、2例(33%)特发性vf患者、3例(50%)COCM患者和1例(50%)HOCM患者中。我们的数据表明,无冠心病的smvt或vf患者预后良好。然而,这些患者室性心律失常复发的发生率很高。