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[猫异相睡眠期间下丘脑后部的血流与氧分压]

[Blood flow and pO2 in the posterior hypothalamus of cats during paradoxical sleep].

作者信息

Nikolaĭshvili L S, Gobechiia L Sh, Devdariani M I

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1989 May-Jun;39(3):536-42.

PMID:2800702
Abstract

In chronic experiments on cats it has been found by recording of the brain local blood flow (BLBF) and of oxygen tension (pO2) in the posterior and anterior hypothalamus, that at sleep phases alternation, the changes of these parameters are differently directed: during the paradoxical sleep the level of BLBF and pO2 oscillations frequency increased in the posterior hypothalamus and decreased in the anterior one. During slow-wave sleep opposite relations were observed. Opposite directions of changes of BLBF level and pO2 oscillations frequency in one and the same phase of sleep show that they are of local origin and must be determined by functional-metabolic shifts. In particular, the increase of BLBF level and frequency of pO2 oscillations must reflect a rise of posterior hypothalamus functional-metabolic activity during paradoxical sleep.

摘要

在对猫进行的慢性实验中,通过记录下丘脑后部和前部的脑局部血流量(BLBF)和氧分压(pO2)发现,在睡眠阶段交替时,这些参数的变化方向不同:在异相睡眠期间,下丘脑后部的BLBF水平和pO2振荡频率增加,而在前部则降低。在慢波睡眠期间观察到相反的关系。在同一睡眠阶段,BLBF水平和pO2振荡频率的变化方向相反,表明它们起源于局部,并且一定是由功能代谢变化决定的。特别是,BLBF水平的增加和pO2振荡频率的增加一定反映了异相睡眠期间下丘脑后部功能代谢活动的增强。

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