Human asthma is characterized by more IRF5+ M1 and CD206+ M2 macrophages and less IL-10+ M2-like macrophages around airways compared with healthy airways.
作者信息
Draijer Christina, Boorsma Carian E, Robbe Patricia, Timens Wim, Hylkema Machteld N, Ten Hacken Nick H, van den Berge Maarten, Postma Dirkje S, Melgert Barbro N
机构信息
Department of Pharmacokinetics, Toxicology, and Targeting, Groningen Research Institute for Pharmacy, University of Groningen, Groningen, The Netherlands; Groningen Research Institute for Asthma and COPD, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Groningen Research Institute for Asthma and COPD, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands; Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
出版信息
J Allergy Clin Immunol. 2017 Jul;140(1):280-283.e3. doi: 10.1016/j.jaci.2016.11.020. Epub 2016 Dec 19.
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