Vovin R Ia, Morozov V I, Fakturovich A Ia, Pi'l B N, Golenkov A V, Za'vialov I M
Zh Nevropatol Psikhiatr Im S S Korsakova. 1989;89(7):52-5.
The article presents the data on 57 schizophrenic and 26 neurotic patients investigated by computerized tomography (CT). Only 4 of the neurosis patients (15.4%) displayed minor CT changes. In 45 schizophrenic patients (78.9%) CT changes were detected varying in their markedness. Most frequent were enlargement of cortical sulci (39 patients). Brain ventricles were dilated in 18 patients, cistern, retropineal and retrosellar spaces dilated in 13. Deficit disorders prevailed clinically in patients whose CT scans showed distinct signs of cortical and subcortical atrophy. These patients also had signs of organic pathology accumulated in the early childhood anamnesis. The authors suggest that this was a factor increasing the brain system' susceptibility to destructive impact of endogenous events.
本文呈现了通过计算机断层扫描（CT）对57例精神分裂症患者和26例神经症患者进行调查的数据。神经症患者中只有4例（15.4%）显示出轻微的CT改变。45例精神分裂症患者（78.9%）检测到CT改变，其明显程度各异。最常见的是皮质沟增宽（39例）。18例患者脑室扩张，13例脑池、松果体后和蝶鞍后间隙扩张。CT扫描显示有明显皮质和皮质下萎缩迹象的患者临床上以缺陷障碍为主。这些患者在幼儿期病史中也有累积的器质性病变迹象。作者认为这是一个增加脑系统对内源性事件破坏性影响易感性的因素。
