一项通过计算机断层扫描对精神分裂症患者大脑进行的研究。

A study of schizophrenic brains by computerized tomography scans.

作者信息

Moriguchi I

出版信息

Folia Psychiatr Neurol Jpn. 1981;35(1):55-72. doi: 10.1111/j.1440-1819.1981.tb00201.x.

DOI:10.1111/j.1440-1819.1981.tb00201.x

Abstract

The brains of 55 schizophrenic patients and 65 controls were examined using computerized tomography scans. The width of the interhemispheric fissure and the third ventricle, and the volume of the lateral ventricles in the schizophrenic patients were significantly larger than those obtained in the controls. The extension of the width of the interhemispheric fissure and the increase in the volume of the lateral ventricles in the schizophrenic patients were assumed to be caused not by aging but by the schizophrenic illness itself. The increased in the volume of the lateral ventricles and the area of the anterior horns of the lateral ventricles in the schizophrenic patients was assumed to be related to the schizophrenic pathogenesis.

摘要

使用计算机断层扫描对55名精神分裂症患者和65名对照者的大脑进行了检查。精神分裂症患者的大脑半球间裂宽度、第三脑室宽度以及侧脑室体积均显著大于对照组。精神分裂症患者大脑半球间裂宽度的增大和侧脑室体积的增加被认为不是由衰老引起的，而是由精神分裂症本身导致的。精神分裂症患者侧脑室体积的增加以及侧脑室前角面积的增加被认为与精神分裂症的发病机制有关。