Nurwidya Fariz, Syahruddin Elisna, Yunus Faisal
Department of Pulmonology and Respiratory Medicine, Universitas Indonesia Faculty of Medicine, Jakarta, Indonesia.
Adv Respir Med. 2016;84(6):331-336. doi: 10.5603/ARM.2016.0043.
Lung cancer is the leading cause of cancer-related mortality worldwide. Not only burdened by the limited overall survival, lung cancer patient also suffer from various symptoms, such as pain, that implicated in the quality of life. Cancer pain is a complicated and transiently dynamic symptom that results from multiple mechanisms. This review will describe the pathophysiology of cancer pain and general approach in managing a patient with lung cancer pain. The use of opioids, nonsteroidal anti-inflammatory drugs (NSAIDs), and adjuvant analgesia, as part of the pharmacology therapy along with interventional strategy, will also be discussed.
肺癌是全球癌症相关死亡的主要原因。肺癌患者不仅面临总体生存期有限的负担，还遭受各种症状的折磨，如疼痛，这会影响生活质量。癌痛是一种复杂且动态变化的症状，由多种机制引起。本综述将描述癌痛的病理生理学以及管理肺癌疼痛患者的一般方法。还将讨论阿片类药物、非甾体抗炎药（NSAIDs）和辅助镇痛作为药物治疗一部分以及介入策略的应用。
